Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 7/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | METAP2 | P50579 | 1/20 | 0.47 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.47 |
| ▸ | AXL | P30530 | 1/20 | 0.47 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.47 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21537534 | 0.86 | MAP4K4 (0.59) | MAP4K4KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL24270332 | 0.84 | MAP4K4 (0.74) | MAP4K4KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL16727393 | 0.82 | RAB9A (0.55) | HPGDMETAP2RAB9AHDAC4NPC1 | |
| SCHEMBL3492071 | 0.81 | MAP4K4 (0.53) | MAP4K4KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL15416241 | 0.81 | MAP4K4 (0.53) | MAP4K4KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL2627252 | 0.79 | MAP4K4 (0.60) | MAP4K4KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL27783053 | 0.79 | MEN1 (0.68) | MAP4K4KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL16602145 | 0.78 | NPC1 (0.54) | RAB9AHDAC4NPC1SMN1; SMN2NFKB1 | |
| SCHEMBL12947931 | 0.78 | CYP3A4 (0.54) | MAP4K4KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL2616114 | 0.77 | IDO1 (0.47) | ALDH1A1MAPTLMNARAB9AHDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116283954-A | Hydroxamate compound, preparation method and application thereof | 深圳微芯生物科技股份有限公司 | 2023-06-23 | — | — | CN | disclosed |
| WO-2022117016-A1 | HYDROXAMATE COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 深圳微芯生物科技股份有限公司 | 2022-06-09 | — | — | WO | disclosed |