SCHEMBL29687045

SCHEMBL29687045

O=C(NC1CCC1c1ccc(Cl)cc1Cl)c1cccnc1C(F)(F)F

nearest known ligand 0.42

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ ACKR3 P25106 3/20 0.42
▸ P2RX7 Q99572 6/20 0.41
▸ HCRTR1 O43613 8/20 0.41
▸ HDAC6 Q9UBN7 1/20 0.39
▸ CNR2 P34972 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21273811 1.00 ACKR3 (0.42) ACKR3P2RX7HCRTR1HDAC6CNR2
SCHEMBL21273819 1.00 ACKR3 (0.42) ACKR3P2RX7HCRTR1HDAC6CNR2
SCHEMBL29367888 1.00 ACKR3 (0.42) ACKR3P2RX7HCRTR1HDAC6CNR2
SCHEMBL16372435 1.00 ACKR3 (0.42) ACKR3P2RX7HCRTR1HDAC6CNR2
SCHEMBL30704818 1.00 ACKR3 (0.42) ACKR3P2RX7HCRTR1HDAC6CNR2
SCHEMBL24543387 1.00 ACKR3 (0.42) ACKR3P2RX7HCRTR1HDAC6CNR2
SCHEMBL19771728 1.00 ACKR3 (0.42) ACKR3P2RX7HCRTR1HDAC6CNR2
Water SCHEMBL22686581 0.99 ACKR3 (0.42) ACKR3P2RX7HCRTR1HDAC6CNR2
Water SCHEMBL30477660 0.99 ACKR3 (0.42) ACKR3P2RX7HCRTR1HDAC6CNR2
Water SCHEMBL28425272 0.99 ACKR3 (0.42) ACKR3P2RX7HCRTR1HDAC6CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4255189-B1 MIXTURES CONTAINING METARYLPICOXAMID BASF SE (DE) 2024-10-30 — — EP claimed
CN-118140927-A Sterilization insecticidal composition containing quinolone compounds and application thereof 潍坊中农联合化工有限公司 2024-06-07 — — CN claimed
US-20240016150-A1 MIXTURES CONTAINING METARYLPICOXAMID BASF SE (DE) 2024-01-18 — — US claimed
EP-4255189-A1 MIXTURES CONTAINING METARYLPICOXAMID BASF SE (DE) 2023-10-11 — — EP claimed
WO-2022117373-A1 MIXTURES CONTAINING METARYLPICOXAMID BASF SE (DE) 2022-06-09 — — WO claimed
CN-116210701-B Pesticide composition and application thereof 青岛滕润翔检测评价有限公司 2025-06-17 — — CN disclosed
CN-115777713-B Nematicidal composition and application thereof 青岛海利尔生物科技有限公司 2025-05-30 — — CN disclosed
EP-4451871-A1 HIGH TEMPERATURE-STABLE AGROCHEMICAL COMPOSITION Syngenta Crop Protection AG (CH) 2024-10-30 — — EP disclosed
CN-118510393-A High temperature stable agrochemical composition 先正达农作物保护股份公司 2024-08-16 — — CN disclosed
CN-118140927-A Sterilization insecticidal composition containing quinolone compounds and application thereof 潍坊中农联合化工有限公司 2024-06-07 — — CN disclosed
CN-111741945-B Crystalline forms 先正达参股股份有限公司 2024-01-09 — — CN disclosed
CN-116806836-B Nematicide composition, nematicide and application of nematicide 山东科大创业生物有限公司 2023-11-21 — — CN disclosed
CN-116806836-A Nematicide composition, nematicide and application of nematicide 山东科大创业生物有限公司 2023-09-29 — — CN disclosed
CN-116709921-A Method for expelling harmful annelid using natural pyrethrin 住友化学株式会社 2023-09-05 — — CN disclosed
CN-116456817-A Heterocyclic compound and harmful arthropod control composition containing same 住友化学株式会社 2023-07-18 — — CN disclosed
CN-116456818-A Heterocyclic compound and harmful arthropod control composition containing same 住友化学株式会社 2023-07-18 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240016150-A1 MIXTURES CONTAINING METARYLPICOXAMID MTX1, MTX2, METAP1 ACKR3 4364/4885P2RX7 48/4885HCRTR1 1259/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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