SCHEMBL29688166

SCHEMBL29688166

Cc1ccc(C)c(B2OC(C)(C)C(C)(C)O2)c1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LPL P06858 11/20 0.36
LIPG Q9Y5X9 11/20 0.36
TDP1 Q9NUW8 3/20 0.35
ALDH1A1 P00352 2/20 0.35
MAPK1 P28482 1/20 0.34
KDM4E B2RXH2 1/20 0.33
LMNA P02545 1/20 0.33
HTT P42858 1/20 0.33
P2RX7 Q99572 1/20 0.32
TP53 P04637 2/20 0.32
CYP3A4 P08684 1/20 0.32
THRB P10828 1/20 0.32
ALOX15 P16050 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
HIF1A Q16665 1/20 0.32
CYP1A2 P05177 1/20 0.31
CYP2A6 P11509 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA9 Q16790 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4827664 1.00 LPL (0.36) LPLLIPGTDP1ALDH1A1MAPK1
SCHEMBL7162437 0.84 LPL (0.38) LPLLIPGTDP1ALDH1A1KDM4E
SCHEMBL29424563 0.84 LPL (0.38) LPLLIPGTDP1ALDH1A1KDM4E
SCHEMBL3191098 0.82 TDP1 (0.45) LPLLIPGTDP1ALDH1A1MAPK1
SCHEMBL15553966 0.81 LPL (0.32) LPLLIPGALDH1A1HIF1A
SCHEMBL18039553 0.81 ACHE (0.37) LPLLIPGALDH1A1MAPK1KDM4E
SCHEMBL1753525 0.81 TRPA1 (0.43) LPLLIPGTDP1ALDH1A1KDM4E
SCHEMBL22715907 0.81 LPL (0.34) LPLLIPGMAPK1P2RX7
Hydrochloric Acid SCHEMBL16753825 0.81 TDP1 (0.43) LPLLIPGTDP1ALDH1A1MAPK1
SCHEMBL17443668 0.81 LPL (0.41) LPLLIPGALDH1A1P2RX7HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109415344-B Metal complexes 默克专利有限公司 2022-06-03 CN disclosed