Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 14/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20243474 | 1.00 | PIK3CD (0.46) | PIK3CDPTGS2ALDH1A1LMNAMAPT | |
| SCHEMBL20246650 | 0.86 | PIK3CD (0.45) | PIK3CDALDH1A1LMNAMAPTTDP1 | |
| SCHEMBL29688362 | 0.86 | PIK3CD (0.45) | PIK3CDALDH1A1LMNAMAPTTDP1 | |
| SCHEMBL20243468 | 0.85 | PIK3CD (0.43) | PIK3CDALDH1A1LMNAMAPTTDP1 | |
| SCHEMBL29688618 | 0.85 | PIK3CD (0.43) | PIK3CDALDH1A1LMNAMAPTTDP1 | |
| SCHEMBL20255005 | 0.83 | PTGS2 (0.43) | PTGS2 | |
| SCHEMBL20254943 | 0.83 | PIK3CD (0.44) | PIK3CDALDH1A1LMNAMAPTTDP1 | |
| SCHEMBL23880075 | 0.82 | PIK3CD (0.38) | PIK3CDPTGS2 | |
| SCHEMBL20254967 | 0.81 | PIK3CD (0.42) | PIK3CD | |
| SCHEMBL29688420 | 0.81 | PIK3CD (0.42) | PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110267959-B | Imidazo [1,5-A ] pyrazine derivatives as PI3K delta inhibitors | 百济神州有限公司 | 2022-05-27 | — | — | CN | disclosed |