Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | MMP14 | P50281 | 1/20 | 0.42 |
| ▸ | TNKS | O95271 | 1/20 | 0.39 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.36 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.36 |
| ▸ | TNF | P01375 | 1/20 | 0.35 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20134959 | 1.00 | LMNA (0.52) | LMNAMEN1KMT2AMMP8MMP14 | |
| SCHEMBL20134957 | 1.00 | LMNA (0.52) | LMNAMEN1KMT2AMMP8MMP14 | |
| SCHEMBL542805 | 0.87 | LMNA (0.55) | LMNAMEN1KMT2AMMP8MMP14 | |
| SCHEMBL20135343 | 0.81 | LMNA (0.52) | LMNAMEN1KMT2ATNKSTNF | |
| SCHEMBL20135551 | 0.81 | LMNA (0.52) | LMNAMEN1KMT2ATNKSTNF | |
| SCHEMBL542150 | 0.80 | LMNA (0.59) | LMNAMEN1KMT2ATNKSTNF | |
| SCHEMBL29949272 | 0.79 | LMNA (0.51) | LMNAMEN1KMT2AMMP14TNKS | |
| SCHEMBL542616 | 0.79 | LMNA (0.51) | LMNAMEN1KMT2AMMP8MMP14 | |
| SCHEMBL20135230 | 0.79 | LMNA (0.48) | LMNAMEN1KMT2ATNKS | |
| SCHEMBL20134743 | 0.79 | LMNA (0.48) | LMNAMEN1KMT2ATNKS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107922347-B | Novel imide derivatives and their use as pharmaceuticals | 田边三菱制药株式会社 | 2022-06-28 | — | — | CN | disclosed |