Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAMTS5 | Q9UNA0 | 14/20 | 0.64 |
| ▸ | HTT | P42858 | 4/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | ADAM17 | P78536 | 8/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | MMP1 | P03956 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | MMP13 | P45452 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29688675 | 1.00 | ADAMTS5 (0.64) | ADAMTS5HTTPOLBADAM17LMNA | |
| SCHEMBL29689198 | 1.00 | ADAMTS5 (0.64) | ADAMTS5HTTPOLBADAM17LMNA | |
| SCHEMBL20135605 | 1.00 | ADAMTS5 (0.64) | ADAMTS5HTTPOLBADAM17LMNA | |
| SCHEMBL20135522 | 1.00 | ADAMTS5 (0.64) | ADAMTS5HTTPOLBADAM17LMNA | |
| SCHEMBL20135430 | 1.00 | ADAMTS5 (0.64) | ADAMTS5HTTPOLBADAM17LMNA | |
| SCHEMBL29688845 | 0.92 | ADAMTS5 (0.67) | ADAMTS5HTTPOLBADAM17LMNA | |
| SCHEMBL20135711 | 0.92 | ADAMTS5 (0.67) | ADAMTS5HTTPOLBADAM17LMNA | |
| SCHEMBL20134780 | 0.91 | ADAMTS5 (0.65) | ADAMTS5HTTPOLBADAM17LMNA | |
| SCHEMBL29689082 | 0.91 | ADAMTS5 (0.65) | ADAMTS5HTTPOLBADAM17LMNA | |
| SCHEMBL20135179 | 0.90 | ADAMTS5 (0.61) | ADAMTS5HTTPOLBADAM17LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107922347-B | Novel imide derivatives and their use as pharmaceuticals | 田边三菱制药株式会社 | 2022-06-28 | — | — | CN | disclosed |