Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 6/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ADAMTS5 | Q9UNA0 | 9/20 | 0.36 |
| ▸ | ADAM17 | P78536 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20135396 | 1.00 | GBA1 (0.38) | GBA1LMNAADAMTS5ADAM17HTT | |
| SCHEMBL20135354 | 0.92 | HTT (0.43) | GBA1LMNAADAMTS5ADAM17HTT | |
| SCHEMBL29689076 | 0.92 | HTT (0.43) | GBA1LMNAADAMTS5ADAM17HTT | |
| SCHEMBL20135352 | 0.92 | HTT (0.43) | GBA1LMNAADAMTS5ADAM17HTT | |
| SCHEMBL29688820 | 0.92 | HTT (0.43) | GBA1LMNAADAMTS5ADAM17HTT | |
| SCHEMBL29688920 | 0.92 | HTT (0.43) | GBA1LMNAADAMTS5ADAM17HTT | |
| SCHEMBL20135445 | 0.92 | HTT (0.43) | GBA1LMNAADAMTS5ADAM17HTT | |
| SCHEMBL20134796 | 0.90 | ALDH1A1 (0.39) | GBA1LMNAADAMTS5ADAM17HTT | |
| SCHEMBL29688482 | 0.90 | ALDH1A1 (0.39) | GBA1LMNAADAMTS5ADAM17HTT | |
| SCHEMBL20134799 | 0.90 | ALDH1A1 (0.39) | GBA1LMNAADAMTS5ADAM17HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107922347-B | Novel imide derivatives and their use as pharmaceuticals | 田边三菱制药株式会社 | 2022-06-28 | — | — | CN | disclosed |