Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20135145 | 1.00 | KDM4E (0.49) | KDM4EHPGDSMN1; SMN2NPSR1RXFP1 | |
| SCHEMBL17973677 | 0.88 | HPGD (0.47) | KDM4EHPGDSMN1; SMN2NPSR1HSD17B10 | |
| SCHEMBL20505374 | 0.82 | TSHR (0.61) | KDM4EHPGDSMN1; SMN2NPSR1RXFP1 | |
| SCHEMBL29688832 | 0.82 | ALDH1A1 (0.47) | KDM4EHPGDSMN1; SMN2HIF1AHSD17B10 | |
| SCHEMBL3484524 | 0.82 | ALDH1A1 (0.47) | KDM4EHPGDSMN1; SMN2HIF1AHSD17B10 | |
| SCHEMBL4584625 | 0.82 | TSHR (0.60) | KDM4EHPGDTSHRHSD17B10CYP3A4 | |
| SCHEMBL7345060 | 0.81 | KDM4E (0.51) | KDM4EHPGDSMN1; SMN2NPSR1RXFP1 | |
| SCHEMBL17375390 | 0.81 | MKNK1 (0.53) | KDM4EHPGDSMN1; SMN2TSHRHSD17B10 | |
| SCHEMBL28591655 | 0.80 | NPSR1 (0.39) | KDM4EHPGDSMN1; SMN2NPSR1KMT2A | |
| SCHEMBL20135292 | 0.80 | TSHR (0.59) | KDM4ESMN1; SMN2TSHRLMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107922347-B | Novel imide derivatives and their use as pharmaceuticals | 田边三菱制药株式会社 | 2022-06-28 | — | — | CN | disclosed |