Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.37 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.37 |
| ▸ | ADAMTS5 | Q9UNA0 | 12/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | ADAM17 | P78536 | 6/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | CPS1 | P31327 | 1/20 | 0.34 |
| ▸ | GBA1 | P04062 | 1/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20134791 | 1.00 | HTT (0.40) | HTTKMT2ALMNAMAPTTSHR | |
| SCHEMBL20135670 | 0.90 | HTT (0.37) | HTTKMT2AKDM4ESLC6A9SLC6A5 | |
| SCHEMBL29689083 | 0.90 | HTT (0.37) | HTTKMT2AKDM4ESLC6A9SLC6A5 | |
| SCHEMBL29688943 | 0.88 | HTT (0.42) | HTTKMT2ALMNAMAPTTSHR | |
| SCHEMBL29688198 | 0.88 | HTT (0.42) | HTTKMT2ALMNAMAPTTSHR | |
| SCHEMBL20135398 | 0.88 | HTT (0.42) | HTTKMT2ALMNAMAPTTSHR | |
| SCHEMBL20135402 | 0.88 | HTT (0.42) | HTTKMT2ALMNAMAPTTSHR | |
| SCHEMBL29688993 | 0.87 | HTT (0.40) | HTTKMT2ALMNAMAPTTSHR | |
| SCHEMBL20135075 | 0.87 | HTT (0.40) | HTTKMT2ALMNAMAPTTSHR | |
| SCHEMBL20134989 | 0.87 | ALDH1A1 (0.40) | HTTKMT2ALMNAMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107922347-B | Novel imide derivatives and their use as pharmaceuticals | 田边三菱制药株式会社 | 2022-06-28 | — | — | CN | disclosed |