SCHEMBL29689072

SCHEMBL29689072

O=C1NS(=O)(=O)c2c1ccc(F)c2Br

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 13/20 0.39
CA9 Q16790 13/20 0.39
CA2 P00918 11/20 0.39
CA7 P43166 7/20 0.39
CA1 P00915 5/20 0.39
CA4 P22748 2/20 0.39
KDM4E B2RXH2 1/20 0.39
USP2 O75604 1/20 0.39
LMNA P02545 1/20 0.39
BCHE P06276 1/20 0.39
CA6 P23280 1/20 0.39
CA5A P35218 1/20 0.39
KMT2A Q03164 1/20 0.39
CA14 Q9ULX7 1/20 0.39
CA5B Q9Y2D0 1/20 0.39
CHEK1 O14757 1/20 0.39
DAPK3 O43293 1/20 0.39
MAP4K4 O95819 1/20 0.39
RET P07949 1/20 0.39
PIM1 P11309 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29689272 0.79 CA12 (0.39) CA12CA9CA2CA7CA1
SCHEMBL29689422 0.79 RET (0.46) CA12CA9CA2CA7CA1
SCHEMBL29689648 0.76 CA12 (0.37) CA12CA9CA2CA7CA1
SCHEMBL9442809 0.75 CA12 (0.40) CA12CA9CA2CA7CA1
SCHEMBL29689240 0.75 CA12 (0.36) CA12CA9CA2CA7CA1
SCHEMBL1463156 0.74 CA9 (0.50) CA12CA9CA2CA7CA1
SCHEMBL29689046 0.73 CA12 (0.48) CA12CA9CA2CA7CA1
SCHEMBL29700041 0.71 RET (0.46) CA12CA9CA2CA7CA1
SCHEMBL9617271 0.67 CA12 (0.37) CA12CA9CA2CA7CA1
SCHEMBL2804664 0.67 RET (0.44) CA12CA9CA2CA7CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114671827-B O-benzoyl-sulfonyl imide derivative and application thereof 杭州百新生物医药科技有限公司 2024-09-20 CN disclosed
CN-114671827-A O-benzoylsulfimide derivative and its application 杭州百新生物医药科技有限公司 2022-06-28 CN disclosed