Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT2 | P31751 | 3/20 | 0.54 |
| ▸ | AKT1 | P31749 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CHEK1 | O14757 | 5/20 | 0.45 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | PIM1 | P11309 | 3/20 | 0.44 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.44 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.44 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.42 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.42 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | CLK1 | P49759 | 1/20 | 0.41 |
| ▸ | CLK2 | P49760 | 1/20 | 0.41 |
| ▸ | HIPK1 | Q86Z02 | 1/20 | 0.41 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.41 |
| ▸ | HIPK3 | Q9H422 | 1/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29638874 | 0.93 | AKT2 (0.56) | AKT2AKT1MAPK1CHEK1CHEK2 | |
| SCHEMBL14941606 | 0.83 | PIK3CD (0.52) | AKT2AKT1MAPK1CHEK1CHEK2 | |
| SCHEMBL30737880 | 0.82 | AKT1 (0.48) | AKT2AKT1MAPK1CHEK1CHEK2 | |
| SCHEMBL14896650 | 0.82 | CHEK1 (0.52) | AKT2AKT1MAPK1CHEK1CHEK2 | |
| SCHEMBL9977893 | 0.82 | AKT1 (0.48) | AKT2AKT1MAPK1CHEK1CHEK2 | |
| SCHEMBL16131991 | 0.82 | CCR1 (0.56) | AKT2AKT1MAPK1CHEK1CHEK2 | |
| SCHEMBL15327018 | 0.82 | AKT1 (0.48) | AKT2AKT1MAPK1CHEK1CHEK2 | |
| SCHEMBL30582723 | 0.82 | AKT2 (0.48) | AKT2AKT1MAPK1CHEK1CHEK2 | |
| SCHEMBL26131947 | 0.82 | AKT2 (0.48) | AKT2AKT1MAPK1CHEK1CHEK2 | |
| SCHEMBL16432987 | 0.81 | AKT2 (0.76) | AKT2AKT1PIM1PIM3PIM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116139936-A | Carbonic anhydrase artificial enzyme and preparation method and application thereof | 四川大学 | 2023-05-23 | — | — | CN | claimed |
| CN-116139936-B | Carbonic anhydrase artificial enzyme and preparation method and application thereof | 四川大学 | 2023-07-04 | — | — | CN | disclosed |
| CN-116139936-B | Carbonic anhydrase artificial enzyme and preparation method and application thereof | 四川大学 | 2023-07-04 | — | — | CN | disclosed |
| CN-116139936-A | Carbonic anhydrase artificial enzyme and preparation method and application thereof | 四川大学 | 2023-05-23 | — | — | CN | disclosed |
| CN-116139936-A | Carbonic anhydrase artificial enzyme and preparation method and application thereof | 四川大学 | 2023-05-23 | — | — | CN | disclosed |
| CN-112608492-B | Metal organic framework material of cobalt chain based on double-end pyrazole ligand, preparation and benzene adsorption application | 北京工业大学 | 2022-05-27 | — | — | CN | disclosed |