Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.32 |
| ▸ | PI4KA | P42356 | 1/20 | 0.32 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.32 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.32 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
| ▸ | TEK | Q02763 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3922194 | 0.81 | LMNA (0.56) | LMNABRD4ADORA2API4KAPI4K2B | |
| SCHEMBL29382308 | 0.79 | CYP1A2 (0.44) | LMNADPP4BRD4ADORA2AALDH1A1 | |
| SCHEMBL23579642 | 0.79 | CYP17A1 (0.49) | LMNADPP4BRD4ADORA2APTGDR2 | |
| SCHEMBL23607656 | 0.79 | CYP1A2 (0.44) | LMNADPP4BRD4ADORA2AALDH1A1 | |
| SCHEMBL23579933 | 0.77 | DPP4 (0.54) | DPP4RPS6KA3TEKCYP1A2KMT2A | |
| SCHEMBL23579760 | 0.66 | RPS6KA3 (0.46) | LMNAGRIN2BRPS6KA3MEN1ALDH1A1 | |
| SCHEMBL23608127 | 0.63 | DHODH (0.46) | ADORA2ARPS6KA3MEN1KMT2A | |
| SCHEMBL23579650 | 0.63 | TNF (0.50) | BRD4MEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL114239 | 0.63 | HTR2A (0.37) | LMNAADORA2AALDH1A1CYP1A2HPGD | |
| SCHEMBL23580758 | 0.63 | RPS6KA3 (0.49) | LMNAADORA2ARPS6KA3MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11339150-B2 | Benzimidazole compounds as HDAC6 inhibitors | ONKURE, INC. (US) | 2022-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11339150-B2 | Benzimidazole compounds as HDAC6 inhibitors | HDAC6, HDAC1, HDAC11 | LMNA 1225/4885DPP4 3147/4885GRIN2B 1344/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.