Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 6/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | GPR174 | Q9BXC1 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28943785 | 1.00 | GAA (0.46) | GAAGFERKDM4EPOLBHSD17B10 | |
| SCHEMBL28771928 | 1.00 | GAA (0.46) | GAAGFERKDM4EPOLBHSD17B10 | |
| SCHEMBL13133518 | 0.89 | MAPT (0.50) | GAAGFERHPGDSMN1; SMN2MAPT | |
| SCHEMBL2814598 | 0.89 | MAPT (0.50) | GAAGFERHPGDSMN1; SMN2MAPT | |
| SCHEMBL28771544 | 0.85 | ALOX15 (0.53) | GAAGFERKDM4EHSD17B10HPGD | |
| SCHEMBL28771543 | 0.85 | ALOX15 (0.53) | GAAGFERKDM4EHSD17B10HPGD | |
| SCHEMBL13133519 | 0.84 | GAA (0.51) | GAAGFERKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL29690030 | 0.84 | GAA (0.51) | GAAGFERKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL28771639 | 0.84 | GAA (0.51) | GAAGFERKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL1479064 | 0.83 | GFER (0.46) | GAAGFERKDM4EPOLBHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114891003-B | Novel dihydropyrimidine compound, intermediate or salt, and preparation method and application thereof | 成都施贝康生物医药科技有限公司 | 2023-10-13 | — | — | CN | disclosed |
| CN-114656472-B | Pyrazolopyrimidine compound, isomer or salt, and preparation method and application thereof | 成都施贝康生物医药科技有限公司 | 2023-07-04 | — | — | CN | disclosed |
| CN-114891003-A | Novel dihydropyrimidine compounds, intermediates or salts, and preparation method and application thereof | 成都施贝康生物医药科技有限公司 | 2022-08-12 | — | — | CN | disclosed |
| CN-114671875-A | Novel dihydropyrimidine compound, isomer or salt, and preparation method and application thereof | 成都施贝康生物医药科技有限公司 | 2022-06-28 | — | — | CN | disclosed |
| CN-114656472-A | Pyrazolopyrimidine compound, isomer or salt, and preparation method and application thereof | 成都施贝康生物医药科技有限公司 | 2022-06-24 | — | — | CN | disclosed |