Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHB3 | P54753 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | G6PD | P11413 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | PSD | A5PKW4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4256814 | 0.84 | KMT2A (0.58) | EPHB3GAAALDH1A1POLBKDM4E | |
| SCHEMBL8312175 | 0.81 | EPHB3 (0.49) | EPHB3GAAALDH1A1POLBKDM4E | |
| SCHEMBL954716 | 0.81 | EPHB3 (0.57) | EPHB3GAAALDH1A1POLBKDM4E | |
| SCHEMBL954299 | 0.79 | EPHB3 (0.56) | EPHB3GAAALDH1A1POLBKDM4E | |
| SCHEMBL953778 | 0.79 | EPHB3 (0.50) | EPHB3GAAALDH1A1POLBKDM4E | |
| SCHEMBL12850522 | 0.79 | EPHB3 (0.60) | EPHB3GAAALDH1A1POLBKDM4E | |
| SCHEMBL29689941 | 0.78 | ALDH1A1 (0.39) | EPHB3GAAALDH1A1POLBKDM4E | |
| SCHEMBL975608 | 0.75 | GAA (0.58) | EPHB3GAAALDH1A1POLBKDM4E | |
| SCHEMBL18766608 | 0.75 | EPHB3 (0.58) | EPHB3GAAALDH1A1POLBKDM4E | |
| SCHEMBL6223693 | 0.75 | MAPK1 (0.63) | EPHB3ALDH1A1POLBKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114605390-B | Compounds having CDK kinase inhibitory activity, pharmaceutical compositions and uses thereof | 上海凌达生物医药有限公司 | 2024-08-16 | — | — | CN | disclosed |
| CN-114605390-A | Compound with CDK kinase inhibitory activity, pharmaceutical composition and use thereof | 上海凌达生物医药有限公司 | 2022-06-10 | — | — | CN | disclosed |