Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 20/20 | 1.00 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | SNCA | P37840 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11994271 | 1.00 | APP (1.00) | APPMAPTSNCA | |
| SCHEMBL12973263 | 0.89 | APP (0.83) | APPMAPTSNCA | |
| SCHEMBL11303203 | 0.89 | APP (0.83) | APPMAPTSNCA | |
| SCHEMBL25304689 | 0.85 | APP (0.74) | APP | |
| SCHEMBL24133448 | 0.85 | APP (0.74) | APP | |
| SCHEMBL24133648 | 0.85 | APP (0.74) | APP | |
| SCHEMBL2835377 | 0.84 | APP (1.00) | APPMAPTSNCA | |
| Florbetaben SCHEMBL12641432 | 0.84 | APP (1.00) | APPMAPTSNCA | |
| SCHEMBL2836082 | 0.84 | APP (1.00) | APPMAPTSNCA | |
| SCHEMBL2832329 | 0.84 | APP (1.00) | APPMAPTSNCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4663637-A2 | NOVEL DEUTERIUM SUBSTITUTED POSITRON EMISSION TOMOGRAPHY (PET) IMAGING AGENTS AND THEIR PHARMACOLOGICAL APPLICATION | Five Eleven Pharma Inc. (US) | 2025-12-17 | — | — | EP | disclosed |
| EP-3630757-B1 | NOVEL DEUTERIUM SUBSTITUTED POSITRON EMISSION TOMOGRAPHY (PET) IMAGING AGENTS AND THEIR PHARMACOLOGICAL APPLICATION | FIVE ELEVEN PHARMA INC (US) | 2025-11-05 | — | — | EP | disclosed |
| CN-119053573-A | Deuterated imidazole kesheng and methods of use thereof | 人类生物科学股份有限公司 | 2024-11-29 | — | — | CN | disclosed |
| CN-114539243-B | Novel deuterium-substituted Positron Emission Tomography (PET) imaging agent and pharmacological application thereof | 五一一制药股份有限公司 | 2024-01-30 | — | — | CN | disclosed |
| CN-113226381-B | Naphthalene derivative conjugated metal oxide nanoparticles as contrast agents for detection of beta-amyloid plaques by magnetic resonance imaging | 古巴神经科学中心 | 2023-09-19 | — | — | CN | disclosed |
| CN-115536580-A | Deuterium substituted Positron Emission Tomography (PET) imaging agents and their pharmacological use | 五一一制药股份有限公司 | 2022-12-30 | — | — | CN | disclosed |
| CN-110678465-B | Novel deuterium-substituted Positron Emission Tomography (PET) imaging agents and their pharmacological use | 五一一制药股份有限公司 | 2022-12-02 | — | — | CN | disclosed |
| EP-3166610-B1 | METHODS FOR TREATING NEUROLOGIC DISORDERS | EIP PHARMA LLC (US) | 2022-11-02 | — | — | EP | disclosed |
| EP-3368040-B1 | METHODS AND COMPOSITIONS FOR RECOVERY FROM STROKE | EIP PHARMA LLC (US) | 2022-08-17 | — | — | EP | disclosed |
| CN-114539243-A | Novel deuterium-substituted Positron Emission Tomography (PET) imaging agents and their pharmacological use | 五一一制药股份有限公司 | 2022-05-27 | — | — | CN | disclosed |