Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 15/20 | 0.74 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | HTR1B | P28222 | 1/20 | 0.47 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.45 |
| ▸ | CHRNA10 | Q9GZZ6 | 2/20 | 0.45 |
| ▸ | CHRNA9 | Q9UGM1 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29690309 | 0.85 | APP (1.00) | APP | |
| SCHEMBL24133648 | 0.85 | APP (0.74) | APP | |
| SCHEMBL11994271 | 0.85 | APP (1.00) | APP | |
| SCHEMBL25304689 | 0.85 | APP (0.74) | APP | |
| SCHEMBL13827086 | 0.84 | APP (0.74) | APP | |
| SCHEMBL12973266 | 0.80 | APP (0.68) | APP | |
| SCHEMBL12973263 | 0.80 | APP (0.83) | APP | |
| SCHEMBL11303203 | 0.80 | APP (0.83) | APP | |
| SCHEMBL19327366 | 0.80 | HTR1B (0.71) | L3MBTL1HTR1BCHRNA7CHRNA10CHRNA9 | |
| SCHEMBL19327367 | 0.80 | HTR1B (0.71) | L3MBTL1HTR1BCHRNA7CHRNA10CHRNA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021257650-A1 | TARGETED ABERRANT ALPHA-SYNUCLEIN SPECIES AND INDUCED UBIQUITINATION AND PROTEOSOMAL CLEARANCE VIA CO-RECRUITMENT OF AN E3-LIGASE SYSTEM | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2021-12-23 | — | — | WO | disclosed |