Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 13/20 | 0.33 |
| ▸ | S100A4 | P26447 | 1/20 | 0.33 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9927121 | 0.95 | LMNA (0.39) | KDM4EMEN1LMNAMAPTOPRK1 | |
| SCHEMBL132981 | 0.95 | LMNA (0.39) | KDM4EMEN1LMNAMAPTOPRK1 | |
| SCHEMBL12016691 | 0.95 | LMNA (0.39) | KDM4EMEN1LMNAMAPTOPRK1 | |
| SCHEMBL17928303 | 0.95 | LMNA (0.39) | KDM4EMEN1LMNAMAPTOPRK1 | |
| SCHEMBL132071 | 0.95 | LMNA (0.39) | KDM4EMEN1LMNAMAPTOPRK1 | |
| SCHEMBL29865503 | 0.95 | LMNA (0.39) | KDM4EMEN1LMNAMAPTOPRK1 | |
| SCHEMBL29511972 | 0.95 | LMNA (0.39) | KDM4EMEN1LMNAMAPTOPRK1 | |
| SCHEMBL29842660 | 0.95 | LMNA (0.39) | KDM4EMEN1LMNAMAPTOPRK1 | |
| SCHEMBL30807114 | 0.95 | LMNA (0.39) | KDM4EMEN1LMNAMAPTOPRK1 | |
| SCHEMBL11991037 | 0.90 | PDK2 (0.42) | KDM4EMEN1LMNAMAPTOPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7776455-B2 | Organic electronic devices | MERCK PATENT GMBH (DE) | 2010-08-17 | — | — | US | disclosed |
| US-7776455-B2 | Organic electronic devices | MERCK PATENT GMBH (DE) | 2010-08-17 | — | — | US | disclosed |
| US-7776455-B2 | Organic electronic devices | MERCK PATENT GMBH (DE) | 2010-08-17 | — | — | US | disclosed |
| US-20070170419-A1 | Organic electronic devices | MERCK PATENT GMBH (DE) | 2007-07-26 | — | — | US | disclosed |
| US-20070170419-A1 | Organic electronic devices | MERCK PATENT GMBH (DE) | 2007-07-26 | — | — | US | disclosed |
| US-20070170419-A1 | Organic electronic devices | MERCK PATENT GMBH (DE) | 2007-07-26 | — | — | US | disclosed |