Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 15/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.47 |
| ▸ | HPGD | P15428 | 6/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 10/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 9/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 8/20 | 0.41 |
| ▸ | USP2 | O75604 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17135754 | 0.77 | HSD17B10 (0.69) | HSD17B10ALDH1A1HPGDCYP2D6CYP3A4 | |
| SCHEMBL29690827 | 0.71 | CYP2C9 (0.37) | HSD17B10ALDH1A1CYP2D6CYP3A4USP2 | |
| SCHEMBL3195427 | 0.70 | SORD (0.43) | ALDH1A1USP2TSHRMAPK1 | |
| SCHEMBL9803609 | 0.70 | SORD (0.43) | HSD17B10ALDH1A1CYP2D6CYP1A2USP2 | |
| SCHEMBL9418619 | 0.69 | SORD (0.50) | ALDH1A1USP2 | |
| SCHEMBL3192090 | 0.69 | SORD (0.42) | HPGDUSP2ALOX15 | |
| SCHEMBL3197967 | 0.69 | SORD (0.42) | HPGDUSP2ALOX15 | |
| SCHEMBL724177 | 0.69 | SORD (0.42) | HPGDUSP2ALOX15 | |
| SCHEMBL23228690 | 0.67 | HSD17B10 (0.40) | HSD17B10ALDH1A1HPGDCYP2D6CYP3A4 | |
| SCHEMBL23228760 | 0.64 | TSHR (0.34) | HSD17B10ALDH1A1HPGDCYP2D6CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114555592-B | 2-Azaspiro [3.4] octane derivatives as M4 agonists | 诺华股份有限公司 | 2024-09-06 | — | — | CN | claimed |
| CN-114555592-A | 2-azaspiro [3.4] octane derivatives as M4 agonists | 诺华股份有限公司 | 2022-05-27 | — | — | CN | claimed |
| CN-114555592-B | 2-Azaspiro [3.4] octane derivatives as M4 agonists | 诺华股份有限公司 | 2024-09-06 | — | — | CN | disclosed |
| CN-114555592-A | 2-azaspiro [3.4] octane derivatives as M4 agonists | 诺华股份有限公司 | 2022-05-27 | — | — | CN | disclosed |