Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 4/20 | 0.54 |
| ▸ | DAO | P14920 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.40 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.40 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.37 |
| ▸ | IGF1R | P08069 | 1/20 | 0.37 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.37 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.37 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.37 |
| ▸ | FEN1 | P39748 | 1/20 | 0.37 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | CNOT7 | Q9UIV1 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1699090 | 0.86 | DAO (0.62) | TNKSDAOKMT2AMEN1LMNA | |
| SCHEMBL30565799 | 0.82 | NTRK1 (0.56) | TNKSDAOKMT2AMEN1LMNA | |
| SCHEMBL16456362 | 0.79 | DAO (0.54) | TNKSDAOKMT2AMEN1LMNA | |
| SCHEMBL16455946 | 0.76 | TNKS (0.51) | TNKSDAOKMT2AMEN1LMNA | |
| SCHEMBL16456333 | 0.76 | TNKS (0.51) | TNKSDAOKMT2AMEN1CDK5 | |
| SCHEMBL23119573 | 0.74 | CDK5 (0.59) | TNKSDAOKMT2AMEN1LMNA | |
| SCHEMBL16657373 | 0.72 | TNKS (0.52) | TNKSDAOKMT2AMEN1LMNA | |
| SCHEMBL21463894 | 0.72 | DAO (0.49) | TNKSDAOKMT2AMEN1LMNA | |
| SCHEMBL30615461 | 0.72 | DAO (0.49) | TNKSDAOKMT2AMEN1LMNA | |
| SCHEMBL21463329 | 0.71 | DAO (0.51) | TNKSDAOCDK5CDK5R1FEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3414234-B1 | BRUTON'S TYROSINE KINASE INHIBITORS | ZIBO BIOPOLAR CHANGSHENG PHARMACEUTICAL CO LTD (CN) | 2022-06-29 | — | — | EP | disclosed |