Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 8/20 | 0.56 |
| ▸ | NTRK2 | Q16620 | 8/20 | 0.56 |
| ▸ | IGF1R | P08069 | 5/20 | 0.56 |
| ▸ | FGFR1 | P11362 | 5/20 | 0.56 |
| ▸ | NTRK3 | Q16288 | 4/20 | 0.56 |
| ▸ | TNKS | O95271 | 2/20 | 0.54 |
| ▸ | DAO | P14920 | 1/20 | 0.48 |
| ▸ | BLK | P51451 | 2/20 | 0.43 |
| ▸ | LYN | P07948 | 1/20 | 0.43 |
| ▸ | BTK | Q06187 | 1/20 | 0.42 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.41 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18741408 | 0.90 | NTRK1 (0.56) | NTRK1NTRK2IGF1RFGFR1NTRK3 | |
| SCHEMBL1699090 | 0.86 | DAO (0.62) | TNKSDAOMEN1LMNAKMT2A | |
| SCHEMBL28496706 | 0.84 | NTRK1 (0.51) | NTRK1NTRK2IGF1RFGFR1NTRK3 | |
| SCHEMBL29690950 | 0.82 | TNKS (0.54) | NTRK1NTRK2IGF1RFGFR1NTRK3 | |
| SCHEMBL16456362 | 0.79 | DAO (0.54) | TNKSDAOMEN1LMNAKMT2A | |
| SCHEMBL28090539 | 0.78 | NTRK1 (0.55) | NTRK1NTRK2IGF1RFGFR1NTRK3 | |
| Hydrochloric Acid SCHEMBL30760859 | 0.77 | NTRK1 (0.53) | NTRK1NTRK2IGF1RFGFR1NTRK3 | |
| SCHEMBL16456333 | 0.76 | TNKS (0.51) | TNKSDAOMEN1KMT2AMGLL | |
| SCHEMBL16455946 | 0.76 | TNKS (0.51) | TNKSDAOMEN1LMNAKMT2A | |
| SCHEMBL28090395 | 0.75 | NTRK1 (0.55) | NTRK1NTRK2IGF1RFGFR1NTRK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113149983-B | Tyrosine kinase inhibitors | 普林斯匹亚生物制药公司 | 2024-03-29 | — | — | CN | disclosed |
| CN-116710452-A | 4-amino-3- (4-phenoxyphenyl) -1, 3-dihydro-2H-imidazo [4,5-C ] pyridin-2-one derivatives and salts thereof | 建新公司 | 2023-09-05 | — | — | CN | disclosed |