Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 6/20 | 0.46 |
| ▸ | STING1 | Q86WV6 | 10/20 | 0.43 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | STK17B | O94768 | 1/20 | 0.39 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30163694 | 0.82 | STING1 (0.55) | BRD4STING1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL24845338 | 0.82 | STING1 (0.55) | BRD4STING1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL30163788 | 0.80 | BRD4 (0.58) | BRD4STING1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL24845833 | 0.80 | BRD4 (0.58) | BRD4STING1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL29692247 | 0.79 | STING1 (0.52) | BRD4STING1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL22135028 | 0.76 | STING1 (0.64) | STING1CYP3A4 | |
| SCHEMBL21630047 | 0.75 | KDM4E (0.41) | STING1CYP2C9CYP2C19 | |
| SCHEMBL21616395 | 0.74 | STING1 (0.47) | BRD4STING1CSNK1DCYP3A4CYP2D6 | |
| SCHEMBL19448947 | 0.73 | STING1 (0.66) | BRD4STING1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL29867887 | 0.73 | STING1 (0.66) | BRD4STING1CYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112279835-B | Aromatic ring or aromatic heterocyclic imidazole compound, preparation method and pharmaceutical application thereof | 中国医学科学院药物研究所 | 2022-07-22 | — | — | CN | disclosed |