Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 20/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22013072 | 1.00 | NTRK1 (0.37) | NTRK1 | |
| SCHEMBL22013062 | 0.85 | NTRK1 (0.36) | NTRK1 | |
| SCHEMBL22013088 | 0.85 | NTRK1 (0.35) | NTRK1 | |
| SCHEMBL29692793 | 0.85 | CNR2 (0.40) | NTRK1 | |
| SCHEMBL29692817 | 0.85 | ALK (0.42) | NTRK1 | |
| SCHEMBL22013149 | 0.85 | CNR2 (0.40) | NTRK1 | |
| SCHEMBL22013271 | 0.85 | ALK (0.42) | NTRK1 | |
| SCHEMBL22013393 | 0.84 | NTRK1 (0.36) | NTRK1 | |
| SCHEMBL22013396 | 0.84 | NTRK1 (0.38) | NTRK1 | |
| SCHEMBL22013174 | 0.83 | MET (0.39) | NTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113166141-B | Hexa-membered and hexa-membered heterocyclic compounds and application thereof as protein receptor kinase inhibitors | 上海轶诺药业有限公司 | 2022-07-22 | — | — | CN | disclosed |