SCHEMBL296932

SCHEMBL296932

NC(CS)C(=O)NC(CS)C(=O)O

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACE P12821 1/20 0.60
KDM4E B2RXH2 1/20 0.55
MAPT P10636 1/20 0.55
THRB P10828 1/20 0.55
ALOX15 P16050 1/20 0.55
NFKB1 P19838 1/20 0.55
PTGS2 P35354 1/20 0.55
THPO P40225 1/20 0.55
RECQL P46063 1/20 0.55
BLM P54132 1/20 0.55
SMN1; SMN2 Q16637 1/20 0.55
PTGS1 P23219 2/20 0.54
SLC7A11 Q9UPY5 1/20 0.54
FOLH1 Q04609 1/20 0.47
GSTK1 Q9Y2Q3 1/20 0.44
FNTA P49354 5/20 0.43
FNTB P49356 5/20 0.43
PGGT1B P53609 3/20 0.43
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5579254 1.00 ACE (0.60) ACEKDM4EMAPTTHRBALOX15
SCHEMBL296933 1.00 ACE (0.60) ACEKDM4EMAPTTHRBALOX15
SCHEMBL29663240 1.00 ACE (0.60) ACEKDM4EMAPTTHRBALOX15
SCHEMBL5665364 0.96 ACE (0.56) ACEKDM4EMAPTTHRBALOX15
SCHEMBL16770240 0.96 ACE (0.56) ACEKDM4EMAPTTHRBALOX15
SCHEMBL22969994 0.96 ACE (0.56) ACEKDM4EMAPTTHRBALOX15
SCHEMBL7072854 0.96 ACE (0.56) ACEKDM4EMAPTTHRBALOX15
SCHEMBL6809797 0.96 ACE (0.56) ACEKDM4EMAPTTHRBALOX15
SCHEMBL29461530 0.91 ACE (0.51) ACEKDM4EMAPTTHRBALOX15
SCHEMBL30011698 0.91 ACE (0.51) ACEKDM4EMAPTTHRBALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230410977-A1 METHODS AND MATERIALS FOR ASSESSING RADIATION EXPOSURE NUTECH VENTURES 2023-12-21 US claimed
WO-2022140565-A1 METHODS AND MATERIALS FOR ASSESSING RADIATION EXPOSURE NUTECH VENTURES (US) 2022-06-30 WO claimed
US-12161779-B2 Three-dimensional implantable matrix with reduced foreign body response TENSIVE SRL (IT) 2024-12-10 US disclosed
CN-116322813-B Three-dimensional implantable matrix for reducing foreign body response 张力有限责任公司 2024-06-28 CN disclosed
EP-4204029-B1 THREE-DIMENSIONAL IMPLANTABLE MATRIX WITH REDUCED FOREIGN BODY RESPONSE TENSIVE S R L (IT) 2024-04-24 EP disclosed
US-20230410977-A1 METHODS AND MATERIALS FOR ASSESSING RADIATION EXPOSURE NUTECH VENTURES 2023-12-21 US disclosed
US-20230270918-A1 THREE-DIMENSIONAL IMPLANTABLE MATRIX WITH REDUCED FOREIGN BODY RESPONSE TENSIVE SRL (IT) 2023-08-31 US disclosed
EP-4204029-A1 THREE-DIMENSIONAL IMPLANTABLE MATRIX WITH REDUCED FOREIGN BODY RESPONSE Tensive S.r.l. (IT) 2023-07-05 EP disclosed
CN-116322813-A Three-dimensional implantable matrix for reducing foreign body response 张力有限责任公司 2023-06-23 CN disclosed
US-11596693-B2 Antibody-drug conjugates and uses thereof MABPLEX INTERNATIONAL CO., LTD (CN) 2023-03-07 US disclosed
WO-2022140565-A1 METHODS AND MATERIALS FOR ASSESSING RADIATION EXPOSURE NUTECH VENTURES (US) 2022-06-30 WO disclosed
EP-1601735-A1 METHOD OF POLISHING A SILICON-CONTAINING DIELECTRIC Cabot Microelectronics Corporation (US) 2005-12-07 EP disclosed
EP-1432734-A4 CYTOKINE RECEPTOR COMMW SCIENT IND RES ORG (AU) 2005-06-15 EP disclosed
WO-2004069947-A1 METHOD OF POLISHING A SILICON-CONTAINING DIELECTRIC CABOT MICROELECTRONICS CORPORATION (US) 2004-08-19 WO disclosed
US-20040152309-A1 Method of polishing a silicon-containing dielectric CABOT MICROELECTRONICS CORPORATION 2004-08-05 US disclosed
EP-1432734-A1 CYTOKINE RECEPTOR COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2004-06-30 EP disclosed
US-20030211116-A1 Mhc peptides over-expressed on prostate cancer cells and methods of use UNIVERSITY OF VIRGINIA PATENT FOUNDATION 2003-11-13 US disclosed
EP-1303287-A1 MHC PEPTIDES OVER-EXPRESSED ON PROSTATE CANCER CELLS AND METHODS OF USE Argonex Pharmaceuticals (US) 2003-04-23 EP disclosed
WO-2003025017-A1 CYTOKINE RECEPTOR COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2003-03-27 WO disclosed
WO-2001097827-A1 MHC PEPTIDES OVER-EXPRESSED ON PROSTATE CANCER CELLS AND METHODS OF USE ARGONEX PHARMACEUTICALS (US) 2001-12-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11596693-B2 Antibody-drug conjugates and uses thereof DARS1, CD2, FCGR2A ACE 4181/4885KDM4E 3240/4885MAPT 2441/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.