Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | HDAC6 | Q9UBN7 | 9/20 | 0.59 |
| ▸ | HDAC8 | Q9BY41 | 7/20 | 0.59 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.59 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.59 |
| ▸ | CA1 | P00915 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.58 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.51 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.51 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9609808 | 0.83 | SMN1; SMN2 (0.82) | SMN1; SMN2NPC1RAB9AHPGDMAPT | |
| SCHEMBL11658715 | 0.82 | SMN1; SMN2 (0.67) | SMN1; SMN2NPC1RAB9ATP53ALOX15 | |
| SCHEMBL12369268 | 0.81 | MITF (0.64) | SMN1; SMN2NPC1RAB9ATP53ALOX15 | |
| SCHEMBL22335189 | 0.80 | KMT2A (0.56) | SMN1; SMN2NPC1RAB9ATP53ALOX15 | |
| SCHEMBL674669 | 0.80 | NPC1 (0.86) | SMN1; SMN2HDAC6HDAC8HDAC3HDAC11 | |
| SCHEMBL2094519 | 0.80 | SMN1; SMN2 (0.70) | SMN1; SMN2CA1CA2NPC1RAB9A | |
| SCHEMBL3001175 | 0.80 | SMN1; SMN2 (0.64) | SMN1; SMN2CA1CA2NPC1RAB9A | |
| SCHEMBL8886838 | 0.80 | MEN1 (0.69) | SMN1; SMN2CA1CA2NPC1RAB9A | |
| SCHEMBL14880210 | 0.80 | CACNA1B (0.67) | SMN1; SMN2HDAC6HDAC8HDAC3HDAC11 | |
| SCHEMBL15480476 | 0.80 | SMN1; SMN2 (0.70) | SMN1; SMN2HDAC6HDAC8HDAC3HDAC11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220177421-A1 | Process for preparing {6-[(diethylamino)methyl]naphthalen-2-yl}methyl [4-(hydroxycarbamoyl)phenyl]carbamate having high purity | ITALFARMACO SPA (IT) | 2022-06-09 | — | — | US | claimed |
| US-20220177421-A1 | Process for preparing {6-[(diethylamino)methyl]naphthalen-2-yl}methyl [4-(hydroxycarbamoyl)phenyl]carbamate having high purity | ITALFARMACO SPA (IT) | 2022-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220177421-A1 | Process for preparing {6-[(diethylamino)methyl]naphthalen-2-yl}methyl [4-(hydroxycarbamoyl)phenyl]carbamate having high purity | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, CPS1, CYP8B1 | SMN1; SMN2 967/4885HDAC6 3807/4885HDAC8 2012/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.