Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | QPCT | Q16769 | 1/20 | 0.39 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.39 |
| ▸ | ULK1 | O75385 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.36 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.35 |
| ▸ | METAP2 | P50579 | 1/20 | 0.35 |
| ▸ | PLAU | P00749 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 2/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | HCK | P08631 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.34 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.34 |
| ▸ | PRKDC | P78527 | 1/20 | 0.34 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL322170 | 1.00 | GAA (0.53) | GAAQPCTQPCTLULK1CYP1A2 | |
| SCHEMBL1697636 | 0.84 | GAA (0.47) | GAAULK1CYP1A2CRHR1TSHR | |
| SCHEMBL17826394 | 0.82 | GAA (0.49) | GAAULK1CYP1A2 | |
| SCHEMBL9195006 | 0.80 | GAA (0.44) | GAAQPCTQPCTLCYP1A2PLAU | |
| SCHEMBL21995602 | 0.79 | ALDH1A1 (0.43) | GAAULK1CYP1A2TSHRMEN1 | |
| SCHEMBL31366250 | 0.78 | GAA (0.40) | GAAULK1TSHRALDH1A1KMT2A | |
| SCHEMBL13004012 | 0.78 | GAA (0.40) | GAAULK1TSHRALDH1A1KMT2A | |
| SCHEMBL29421576 | 0.78 | CYP1A2 (0.45) | GAACYP1A2EGFRPIK3CATSHR | |
| SCHEMBL21224374 | 0.78 | CYP1A2 (0.45) | GAACYP1A2EGFRPIK3CATSHR | |
| SCHEMBL16815393 | 0.78 | GAA (0.41) | GAAQPCTQPCTLCYP1A2CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-121426750-A | Synthesis method of 2, 4-dichloro-5-cyclopropyl pyrimidine | 凯美克(上海)医药科技有限公司 | 2026-01-30 | — | — | CN | disclosed |
| CN-121405637-A | Synthesis method of 4-chloro-5-cyclopropyl-2-methoxypyrimidine | 上海毕臣生化科技有限公司 | 2026-01-27 | — | — | CN | disclosed |
| CN-119775260-A | Pyrimidine-2, 4 (1H, 3H) -dione compounds, preparation method, pharmaceutical composition and application thereof | 中国医学科学院药物研究所 | 2025-04-08 | — | — | CN | disclosed |
| CN-118666815-A | Preparation method of pseudouridine and N1-methyl pseudouridine | 南京方生和医药科技有限公司 | 2024-09-20 | — | — | CN | disclosed |
| CN-118666815-A | Preparation method of pseudouridine and N1-methyl pseudouridine | 南京方生和医药科技有限公司 | 2024-09-20 | — | — | CN | disclosed |
| WO-2024125451-A1 | PIPERINDIN-ONES DERIVATIVES, PREPARATION METHODS AND MEDICINAL USES THEREOF | JIANGSU HANSOH PHARMACEUTICAL GROUP CO., LTD. (CN) | 2024-06-20 | — | — | WO | disclosed |
| EP-4334320-A1 | SUBSTITUTED SPIRO DERIVATIVES | JANSSEN Pharmaceutica NV (BE) | 2024-03-13 | — | — | EP | disclosed |
| CN-112236416-B | Pyrimidine cyclohexenyl glucocorticoid receptor modulators | 科赛普特治疗公司 | 2024-03-01 | — | — | CN | disclosed |
| CN-117069724-A | Fused ring compounds, pharmaceutical compositions and uses | 上海赛默罗德生物科技有限公司 | 2023-11-17 | — | — | CN | disclosed |
| CN-116813475-A | Halogenated synthesis method of aromatic ring compound | 北京大学 | 2023-09-29 | — | — | CN | disclosed |
| WO-2023285788-A1 | SULFUR COMPOUNDS AND PROCESSES AND INTERMEDIATES USEFUL IN THE PREPARATION THEREOF | OXFORD UNIVERSITY INNOVATION LIMITED (GB) | 2023-01-19 | — | — | WO | disclosed |
| WO-2022237627-A1 | SUBSTITUTED SPIRO DERIVATIVES | JANSSEN PHARMACEUTICA NV (BE) | 2022-11-17 | — | — | WO | disclosed |
| CN-112004845-B | Resin composition, laminate, semiconductor wafer with resin composition layer, substrate, and semiconductor device | 三菱瓦斯化学株式会社 | 2022-05-31 | — | — | CN | disclosed |