SCHEMBL29694582

SCHEMBL29694582

CC(C)[C@H](NC(=O)CNC(=O)CNC(=O)CNC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)N[C@@H](CCCNC(N)=O)C(=O)Nc1ccc(CO)cc1

nearest known ligand 0.48

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ FURIN P09958 2/20 0.39
▸ CASP3 P42574 2/20 0.39
▸ TLR2 O60603 2/20 0.38
▸ PTPN1 P18031 4/20 0.38
▸ KMT2A Q03164 1/20 0.38
▸ MAP1LC3B Q9GZQ8 1/20 0.38
▸ TPSAB1 Q15661 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL84334 0.99 FURIN (0.40) FURINCASP3TLR2PTPN1KMT2A
SCHEMBL13044093 0.92 CASP3 (0.45) FURINCASP3TLR2PTPN1
SCHEMBL10066102 0.92 CASP3 (0.45) FURINCASP3TLR2PTPN1
SCHEMBL29737788 0.92 CASP3 (0.45) FURINCASP3TLR2PTPN1
SCHEMBL13830419 0.92 CASP3 (0.45) FURINCASP3TLR2PTPN1
SCHEMBL84123 0.92 CASP3 (0.45) FURINCASP3TLR2PTPN1
SCHEMBL12944386 0.92 CASP3 (0.45) FURINCASP3TLR2PTPN1
SCHEMBL31371875 0.92 CASP3 (0.45) FURINCASP3TLR2PTPN1
SCHEMBL22387795 0.92 CASP3 (0.45) FURINCASP3TLR2PTPN1
SCHEMBL29407919 0.92 CASP3 (0.45) FURINCASP3TLR2PTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250281630-A1 PHARMACEUTICAL COMPOSITION FOR CANCER TREATMENT AND/OR PREVENTION TORAY INDUSTRIES, INC. (JP) 2025-09-11 — — US disclosed
EP-4580754-A1 AN INTEGRIN ALPHA10 ANTIBODY DRUG CONJUGATE Targinta AB (SE) 2025-07-09 — — EP disclosed
EP-4400121-A1 PHARMACEUTICAL COMPOSITION FOR TREATING AND/OR PREVENTING CANCER Toray Industries, Inc. (JP) 2024-07-17 — — EP disclosed
US-20240100180-A1 TUMOR-SPECIFIC CLAUDIN 18.2 ANTIBODY-DRUG CONJUGATES Sotio Biotech A.S. (CZ) 2024-03-28 — — US disclosed
WO-2024047172-A1 AN INTEGRIN ALPHA10 ANTIBODY DRUG CONJUGATE TARGINTA AB (SE) 2024-03-07 — — WO disclosed
US-20230398232-A1 Composition and Use of Alternatively Formatted Anti-Mesothelin Antibodies for the Treatment of Cancer Navrogen, Inc. 2023-12-14 — — US disclosed
EP-4267194-A1 TUMOR-SPECIFIC CLAUDIN 18.2 ANTIBODY-DRUG CONJUGATES SOTIO Biotech a.s. (CZ) 2023-11-01 — — EP disclosed
CN-116635085-A Tumor specific claudin 18.2 antibody-drug conjugate 斯迪安生物技术公司 2023-08-22 — — CN disclosed
WO-2023033129-A1 PHARMACEUTICAL COMPOSITION FOR TREATING AND/OR PREVENTING CANCER 東レ株式会社 2023-03-09 — — WO disclosed
WO-2022136642-A1 TUMOR-SPECIFIC CLAUDIN 18.2 ANTIBODY-DRUG CONJUGATES Sotio Biotech A.S. (CZ) 2022-06-30 — — WO disclosed
WO-2022122709-A1 ANTIBODY-DRUG CONJUGATES BASED ON HUMANIZED CLDN18.2 ANTIBODIES Sotio Biotech A.S. (CZ) 2022-06-16 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240100180-A1 TUMOR-SPECIFIC CLAUDIN 18.2 ANTIBODY-DRUG CONJUGATES EPCAM, KRT18, DSC1 FURIN 4447/4885CASP3 1120/4885TLR2 755/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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