Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 3/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | F2 | P00734 | 1/20 | 0.54 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.53 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.53 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29349609 | 0.88 | POLB (0.68) | OPRM1POLBF2OPRD1OPRK1 | |
| SCHEMBL29664244 | 0.86 | OPRM1 (0.57) | OPRM1POLBF2OPRD1OPRK1 | |
| SCHEMBL30745226 | 0.86 | F2 (0.55) | OPRM1F2OPRD1OPRK1BDKRB2 | |
| SCHEMBL30310102 | 0.86 | SLC6A2 (0.65) | OPRM1OPRD1OPRK1SLC6A2 | |
| SCHEMBL30574233 | 0.85 | OPRM1 (0.64) | OPRM1OPRD1OPRK1 | |
| SCHEMBL29580824 | 0.84 | POLB (0.56) | OPRM1POLBF2OPRD1OPRK1 | |
| SCHEMBL29531518 | 0.84 | SLC6A2 (0.55) | OPRM1F2OPRD1OPRK1SLC6A2 | |
| SCHEMBL14903336 | 0.84 | OPRM1 (0.57) | OPRM1OPRD1OPRK1 | |
| SCHEMBL14903451 | 0.84 | OPRM1 (0.57) | OPRM1OPRD1OPRK1 | |
| SCHEMBL30957021 | 0.84 | DPP3 (0.59) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4267193-A1 | IMPROVED CD30 TARGETING ANTIBODY DRUG CONJUGATES AND USES THEREOF | Ludwig-Maximilians-Universität München (DE) | 2023-11-01 | — | — | EP | disclosed |
| WO-2022136555-A1 | IMPROVED CD30 TARGETING ANTIBODY DRUG CONJUGATES AND USES THEREOF | LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN (DE) | 2022-06-30 | — | — | WO | disclosed |