Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.48 |
| ▸ | GLO1 | Q04760 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 7/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29597541 | 1.00 | PTGS1 (0.48) | PTGS1GSTK1GLO1ALDH1A1LMNA | |
| SCHEMBL31018947 | 1.00 | PTGS1 (0.48) | PTGS1GSTK1GLO1ALDH1A1LMNA | |
| SCHEMBL30519346 | 1.00 | PTGS1 (0.48) | PTGS1GSTK1GLO1ALDH1A1LMNA | |
| SCHEMBL30674927 | 0.97 | PTGS1 (0.46) | PTGS1GSTK1GLO1ALDH1A1LMNA | |
| SCHEMBL31611850 | 0.97 | PTGS1 (0.50) | PTGS1GSTK1GLO1ALDH1A1LMNA | |
| SCHEMBL29360389 | 0.97 | PTGS1 (0.50) | PTGS1GSTK1GLO1ALDH1A1LMNA | |
| SCHEMBL29671001 | 0.92 | PTGS1 (0.46) | PTGS1GSTK1GLO1ALDH1A1LMNA | |
| SCHEMBL30733592 | 0.92 | PTGS1 (0.46) | PTGS1GSTK1GLO1ALDH1A1LMNA | |
| SCHEMBL265264 | 0.91 | PTGS1 (0.42) | PTGS1GSTK1GLO1OPRD1OPRM1 | |
| SCHEMBL30679729 | 0.91 | PTGS1 (0.42) | PTGS1GSTK1GLO1OPRD1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240124614-A1 | ANTIGEN-BINDING MOLECULES WITH IMPROVED CYTOSOL-PENETRATING ACTIVITY | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2024-04-18 | — | — | US | disclosed |
| EP-4267745-A1 | ANTIGEN-BINDING MOLECULES WITH IMPROVED CYTOSOL-PENETRATING ACTIVITY | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2023-11-01 | — | — | EP | disclosed |
| CN-116715781-A | Recombinant pseudomonas aeruginosa nanoparticle protein reffliC-Ferritin, and preparation method and application thereof | 中国人民解放军陆军军医大学 | 2023-09-08 | — | — | CN | disclosed |
| CN-116648262-A | Antigen binding molecules with improved cytosolic penetration activity | 中外制药株式会社 | 2023-08-25 | — | — | CN | disclosed |
| WO-2023120643-A1 | CXCR3 LIGAND HAVING ENHANCED CXCR3-EXPRESSING CELL MIGRATION ACTIVITY | 中外製薬株式会社 | 2023-06-29 | — | — | WO | disclosed |
| US-20220315909-A1 | PROTEASE SUBSTRATE, AND POLYPEPTIDE INCLUDING PROTEASE CLEAVAGE SEQUENCE | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2022-10-06 | — | — | US | disclosed |
| WO-2022138692-A1 | ANTIGEN-BINDING MOLECULES WITH IMPROVED CYTOSOL-PENETRATING ACTIVITY | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2022-06-30 | — | — | WO | disclosed |