Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.45 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.45 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.41 |
| ▸ | ECE1 | P42892 | 2/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.38 |
| ▸ | MME | P08473 | 4/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31544048 | 0.91 | PDCD1LG2 (0.41) | PDCD1LG2CD274TGFBR1ECE1OPRM1 | |
| SCHEMBL31544014 | 0.91 | PDCD1LG2 (0.41) | PDCD1LG2CD274ECE1OPRM1OPRD1 | |
| SCHEMBL31039962 | 0.90 | PDCD1LG2 (0.46) | PDCD1LG2CD274TGFBR1ECE1OPRM1 | |
| SCHEMBL29630639 | 0.90 | TGFBR1 (0.42) | TGFBR1OPRM1OPRD1OPRK1MME | |
| SCHEMBL31544046 | 0.89 | PDCD1LG2 (0.41) | PDCD1LG2CD274ECE1OPRM1OPRD1 | |
| SCHEMBL31544011 | 0.89 | PDCD1LG2 (0.41) | PDCD1LG2CD274ECE1OPRM1OPRD1 | |
| SCHEMBL31544032 | 0.89 | PDCD1LG2 (0.41) | PDCD1LG2CD274ECE1OPRM1OPRD1 | |
| SCHEMBL31544020 | 0.89 | PDCD1LG2 (0.41) | PDCD1LG2CD274ECE1OPRM1OPRD1 | |
| SCHEMBL31544025 | 0.89 | PDCD1LG2 (0.41) | PDCD1LG2CD274ECE1OPRM1OPRD1 | |
| SCHEMBL31544050 | 0.89 | PDCD1LG2 (0.41) | PDCD1LG2CD274ECE1OPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4267193-A1 | IMPROVED CD30 TARGETING ANTIBODY DRUG CONJUGATES AND USES THEREOF | Ludwig-Maximilians-Universität München (DE) | 2023-11-01 | — | — | EP | disclosed |
| WO-2022136555-A9 | IMPROVED CD30 TARGETING ANTIBODY DRUG CONJUGATES AND USES THEREOF | LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN (DE) | 2022-09-22 | — | — | WO | disclosed |
| WO-2022136555-A1 | IMPROVED CD30 TARGETING ANTIBODY DRUG CONJUGATES AND USES THEREOF | LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN (DE) | 2022-06-30 | — | — | WO | disclosed |