Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | FLT1 | P17948 | 6/20 | 0.38 |
| ▸ | KDR | P35968 | 6/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22925724 | 1.00 | NPSR1 (0.43) | NPSR1KDM4EGSK3BKMT2AFLT1 | |
| Hydrochloric Acid SCHEMBL28733807 | 0.99 | NPSR1 (0.42) | NPSR1KDM4EGSK3BKMT2AFLT1 | |
| SCHEMBL22926119 | 0.88 | GSK3B (0.56) | KDM4EGSK3BKMT2AFLT1KDR | |
| SCHEMBL22925928 | 0.84 | KMT2A (0.40) | NPSR1KDM4EKMT2AFLT1KDR | |
| SCHEMBL28733637 | 0.84 | KMT2A (0.40) | NPSR1KDM4EKMT2AFLT1KDR | |
| SCHEMBL22925799 | 0.84 | RAB9A (0.38) | KDM4EGSK3BKMT2AMAPK1NPC1 | |
| SCHEMBL31013352 | 0.84 | GSK3B (0.37) | KDM4EGSK3BFLT1KDR | |
| SCHEMBL22925558 | 0.84 | GSK3B (0.37) | KDM4EGSK3BFLT1KDR | |
| SCHEMBL28733614 | 0.84 | GSK3B (0.37) | KDM4EGSK3BFLT1KDR | |
| Hydrochloric Acid SCHEMBL29696318 | 0.83 | GSK3B (0.37) | KDM4EGSK3BFLT1KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4003986-A1 | INHIBITOR COMPOUNDS | Cincera Therapeutics Pty Ltd (AU) | 2022-06-01 | — | — | EP | disclosed |