Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCP | P55072 | 5/20 | 0.51 |
| ▸ | SIRT7 | Q9NRC8 | 1/20 | 0.47 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 6/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | FLT1 | P17948 | 5/20 | 0.37 |
| ▸ | FLT4 | P35916 | 4/20 | 0.37 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | FLT3 | P36888 | 1/20 | 0.33 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.33 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.33 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.33 |
| ▸ | RPS6KA1 | Q15418 | 1/20 | 0.33 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.33 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22925695 | 1.00 | VCP (0.51) | VCPSIRT7MAP4K4TRPV1KDR | |
| SCHEMBL28733821 | 1.00 | VCP (0.51) | VCPSIRT7MAP4K4TRPV1KDR | |
| SCHEMBL29696303 | 0.86 | VCP (0.36) | VCPSIRT7KDRF10 | |
| SCHEMBL28733824 | 0.86 | VCP (0.36) | VCPSIRT7KDRF10 | |
| SCHEMBL22925734 | 0.86 | VCP (0.36) | VCPSIRT7KDRF10 | |
| SCHEMBL22925696 | 0.86 | VCP (0.36) | VCPSIRT7KDRF10 | |
| SCHEMBL22925595 | 0.85 | TRPV1 (0.46) | VCPSIRT7TRPV1KDRFLT1 | |
| SCHEMBL28733706 | 0.85 | TRPV1 (0.46) | VCPSIRT7TRPV1KDRFLT1 | |
| SCHEMBL22925699 | 0.84 | VCP (0.60) | VCPSIRT7MAP4K4TRPV1KDR | |
| SCHEMBL29696320 | 0.84 | VCP (0.60) | VCPSIRT7MAP4K4TRPV1KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114450281-B | Inhibitor compounds | 辛塞拉治疗私人有限公司 | 2024-08-16 | — | — | CN | claimed |
| EP-4003986-A1 | INHIBITOR COMPOUNDS | Cincera Therapeutics Pty Ltd (AU) | 2022-06-01 | — | — | EP | disclosed |