Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 12/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 8/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 8/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.36 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.35 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22925487 | 1.00 | HSD11B1 (0.47) | HSD11B1HDAC1HDAC6HDAC8HDAC3 | |
| SCHEMBL22925865 | 0.89 | HSD11B1 (0.51) | HSD11B1ADORA3NLRP3GSTO1 | |
| SCHEMBL22925868 | 0.86 | HSD11B1 (0.46) | HSD11B1ADORA3NLRP3 | |
| SCHEMBL31013378 | 0.83 | HSD11B1 (0.45) | HSD11B1HDAC1HDAC6HDAC8HDAC3 | |
| SCHEMBL22925671 | 0.83 | HSD11B1 (0.45) | HSD11B1HDAC1HDAC6HDAC8HDAC3 | |
| SCHEMBL29621154 | 0.82 | HSD11B1 (0.46) | HSD11B1HDAC4HDAC7HDAC5 | |
| SCHEMBL22925866 | 0.82 | HSD11B1 (0.46) | HSD11B1HDAC4HDAC7HDAC5 | |
| SCHEMBL29696299 | 0.79 | TRPV1 (0.45) | HDAC1HDAC6HDAC8HDAC3HDAC2 | |
| SCHEMBL22925659 | 0.79 | TRPV1 (0.45) | HDAC1HDAC6HDAC8HDAC3HDAC2 | |
| SCHEMBL22925676 | 0.78 | HSD11B1 (0.47) | HSD11B1HDAC1HDAC6HDAC8HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114450281-B | Inhibitor compounds | 辛塞拉治疗私人有限公司 | 2024-08-16 | — | — | CN | claimed |
| CN-114450281-B | Inhibitor compounds | 辛塞拉治疗私人有限公司 | 2024-08-16 | — | — | CN | disclosed |
| EP-4003986-A1 | INHIBITOR COMPOUNDS | Cincera Therapeutics Pty Ltd (AU) | 2022-06-01 | — | — | EP | disclosed |