Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 9/20 | 0.43 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 2/20 | 0.32 |
| ▸ | IKBKB | O14920 | 1/20 | 0.32 |
| ▸ | PLK1 | P53350 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22925892 | 1.00 | TRPV1 (0.43) | TRPV1TRPM8NPSR1IMPDH2ALOX5 | |
| SCHEMBL29696350 | 0.82 | TRPV1 (0.48) | TRPV1NPSR1ALOX5 | |
| SCHEMBL22925745 | 0.82 | TRPV1 (0.48) | TRPV1NPSR1ALOX5 | |
| SCHEMBL22925905 | 0.82 | PPARD (0.41) | TRPV1TRPM8NPSR1IMPDH2GSK3B | |
| SCHEMBL28733796 | 0.82 | PPARD (0.41) | TRPV1TRPM8NPSR1IMPDH2GSK3B | |
| SCHEMBL22925757 | 0.75 | NPSR1 (0.40) | TRPV1NPSR1ALOX5MAPT | |
| Hydrochloric Acid SCHEMBL29696306 | 0.74 | NPSR1 (0.40) | TRPV1NPSR1ALOX5MAPT | |
| SCHEMBL22925727 | 0.73 | TRPV1 (0.49) | TRPV1TRPM8MAPT | |
| SCHEMBL29621013 | 0.73 | TRPV1 (0.49) | TRPV1TRPM8MAPT | |
| SCHEMBL22925746 | 0.72 | NPSR1 (0.38) | TRPV1NPSR1EGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4003986-A1 | INHIBITOR COMPOUNDS | Cincera Therapeutics Pty Ltd (AU) | 2022-06-01 | — | — | EP | disclosed |