Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 6/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.37 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.36 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.35 |
| ▸ | PDE2A | O00408 | 1/20 | 0.35 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.35 |
| ▸ | PLK1 | P53350 | 1/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.35 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.35 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.35 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.35 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.35 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22925905 | 1.00 | PPARD (0.41) | PPARDNPSR1GSK3BTRPV1TRPM8 | |
| SCHEMBL29696304 | 0.87 | IMPDH2 (0.43) | PPARDNPSR1GSK3BTRPV1IMPDH2 | |
| SCHEMBL22926080 | 0.87 | IMPDH2 (0.43) | PPARDNPSR1GSK3BTRPV1IMPDH2 | |
| SCHEMBL22925907 | 0.83 | GSK3B (0.42) | PPARDGSK3BTRPV1IMPDH2PDE2A | |
| SCHEMBL29696327 | 0.82 | TRPV1 (0.43) | NPSR1GSK3BTRPV1TRPM8IMPDH2 | |
| SCHEMBL22925892 | 0.82 | TRPV1 (0.43) | NPSR1GSK3BTRPV1TRPM8IMPDH2 | |
| SCHEMBL29696317 | 0.81 | NPSR1 (0.43) | PPARDNPSR1GSK3BIMPDH2PDE2A | |
| SCHEMBL22925756 | 0.81 | NPSR1 (0.43) | PPARDNPSR1GSK3BIMPDH2PDE2A | |
| SCHEMBL22925796 | 0.78 | IMPDH2 (0.39) | NPSR1IMPDH2 | |
| SCHEMBL29696291 | 0.78 | IMPDH2 (0.39) | NPSR1IMPDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4003986-A1 | INHIBITOR COMPOUNDS | Cincera Therapeutics Pty Ltd (AU) | 2022-06-01 | — | — | EP | disclosed |
| CN-114450281-A | Inhibitor compounds | 辛塞拉治疗私人有限公司 | 2022-05-06 | — | — | CN | disclosed |