Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7772148 | 0.92 | KMT2A (0.43) | TSHRKMT2AYTHDC1SLC6A2SLC6A4 | |
| SCHEMBL7772151 | 0.92 | KMT2A (0.43) | TSHRKMT2AYTHDC1SLC6A2SLC6A4 | |
| SCHEMBL18428792 | 0.85 | YTHDC1 (0.40) | KMT2AYTHDC1SLC6A2SLC6A4ALDH1A1 | |
| SCHEMBL18428790 | 0.85 | YTHDC1 (0.40) | KMT2AYTHDC1SLC6A2SLC6A4ALDH1A1 | |
| SCHEMBL18365044 | 0.85 | YTHDC1 (0.40) | KMT2AYTHDC1SLC6A2SLC6A4ALDH1A1 | |
| SCHEMBL23329876 | 0.83 | YTHDC1 (0.43) | KMT2AYTHDC1SLC6A2SLC6A4ALDH1A1 | |
| SCHEMBL5006779 | 0.83 | YTHDC1 (0.43) | KMT2AYTHDC1SLC6A2SLC6A4ALDH1A1 | |
| SCHEMBL5009994 | 0.83 | YTHDC1 (0.43) | KMT2AYTHDC1SLC6A2SLC6A4ALDH1A1 | |
| SCHEMBL29495252 | 0.83 | YTHDC1 (0.42) | KMT2AYTHDC1SLC6A2SLC6A4ALDH1A1 | |
| Hydrochloric Acid SCHEMBL21222660 | 0.82 | YTHDC1 (0.42) | KMT2AYTHDC1SLC6A2SLC6A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4003980-A1 | HETEROBICYCLIC AMIDES AS INHIBITORS OF CD38 | Ribon Therapeutics Inc. (US) | 2022-06-01 | — | — | EP | disclosed |