SCHEMBL29697216

SCHEMBL29697216

Cc1cc(F)ccc1-c1ccc(N=Nc2cc(S(=O)(=O)O)c3ccccc3c2N)cn1

nearest known ligand 0.82

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ SENP2 Q9HC62 2/20 0.67
▸ SENP1 Q9P0U3 2/20 0.67
▸ SUMO2 P61956 1/20 0.67
▸ SUMO1 P63165 1/20 0.67
▸ SENP7 Q9BQF6 1/20 0.67
▸ SENP3 Q9H4L4 1/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18044286 1.00 SENP2 (0.67) SENP2SENP1SUMO2SUMO1SENP7
SCHEMBL905113 1.00 SENP2 (0.67) SENP2SENP1SUMO2SUMO1SENP7
SCHEMBL14988194 0.99 SENP2 (0.66) SENP2SENP1SUMO2SUMO1SENP7
SCHEMBL14988191 0.99 SENP2 (0.66) SENP2SENP1SUMO2SUMO1SENP7
SCHEMBL15120197 0.93 SENP2 (0.61) SENP2SENP1SUMO2SUMO1SENP7
SCHEMBL29697067 0.93 SENP2 (0.61) SENP2SENP1SUMO2SUMO1SENP7
SCHEMBL18044239 0.93 SENP2 (0.61) SENP2SENP1SUMO2SUMO1SENP7
SCHEMBL14988763 0.92 SENP2 (0.60) SENP2SENP1SUMO2SUMO1SENP7
SCHEMBL14988766 0.92 SENP2 (0.60) SENP2SENP1SUMO2SUMO1SENP7
SCHEMBL17319311 0.91 SENP2 (0.69) SENP2SENP1SUMO2SUMO1SENP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118434418-A Composition for improving cardiac function 国立大学法人京都大学 2024-08-02 — — CN claimed
CN-114599370-A Pharmaceutical composition for protecting cartilage 国立大学法人京都大学 2022-06-07 — — CN claimed
CN-118434418-A Composition for improving cardiac function 国立大学法人京都大学 2024-08-02 — — CN disclosed
CN-114599370-A Pharmaceutical composition for protecting cartilage 国立大学法人京都大学 2022-06-07 — — CN disclosed
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