Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 13/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 7/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL566045 | 1.00 | TLR7 (0.36) | TLR7TLR8MCHR1 | |
| Trifluoroacetic Acid SCHEMBL2199289 | 1.00 | TLR7 (0.36) | TLR7TLR8MCHR1 | |
| SCHEMBL12157746 | 0.89 | TLR7 (0.40) | TLR7TLR8MCHR1 | |
| SCHEMBL1840777 | 0.89 | TLR7 (0.40) | TLR7TLR8MCHR1 | |
| SCHEMBL12157560 | 0.89 | TLR7 (0.40) | TLR7TLR8MCHR1 | |
| Trifluoroacetic Acid SCHEMBL2198204 | 0.88 | AXL (0.34) | TLR7MCHR1 | |
| Trifluoroacetic Acid SCHEMBL434419 | 0.83 | TLR7 (0.33) | TLR7 | |
| Trifluoroacetic Acid SCHEMBL2199668 | 0.83 | ADORA2A (0.34) | — | |
| SCHEMBL10121637 | 0.82 | TLR7 (0.41) | TLR7TLR8 | |
| Trifluoroacetic Acid SCHEMBL566788 | 0.82 | TLR7 (0.39) | TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3218377-B1 | ADENINE DERIVATIVES WHICH ARE USEFUL IN THE TREATMENT OF ALLERGIC DISEASES OR OTHER INFLAMMATORY CONDITIONS | GLAXOSMITHKLINE BIOLOGICALS SA (BE) | 2022-04-13 | — | — | EP | disclosed |