Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.33 |
| ▸ | NOS1 | P29475 | 2/20 | 0.32 |
| ▸ | DPP4 | P27487 | 2/20 | 0.31 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NEK2 | P51955 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL2200389 | 0.90 | NOS1 (0.30) | TLR7NOS1 | |
| Trifluoroacetic Acid SCHEMBL566788 | 0.89 | TLR7 (0.39) | TLR7 | |
| Trifluoroacetic Acid SCHEMBL1146697 | 0.88 | TLR7 (0.37) | TLR7NOS1 | |
| SCHEMBL1146282 | 0.87 | PDE4B (0.34) | TLR7 | |
| Trifluoroacetic Acid SCHEMBL2195624 | 0.86 | S1PR4 (0.30) | — | |
| Trifluoroacetic Acid SCHEMBL2199668 | 0.85 | ADORA2A (0.34) | NOS1 | |
| Trifluoroacetic Acid SCHEMBL2198801 | 0.85 | ADORA2A (0.33) | TLR7 | |
| Trifluoroacetic Acid SCHEMBL2198027 | 0.85 | PDE2A (0.31) | TLR7 | |
| Trifluoroacetic Acid SCHEMBL566045 | 0.83 | TLR7 (0.36) | TLR7 | |
| Trifluoroacetic Acid SCHEMBL29697218 | 0.83 | TLR7 (0.36) | TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012011606-A1 | PROCESS FOR PREPARING ADENINE COMPOUNDS AND INTERMEDIATES THEREOF | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2012-01-26 | — | — | WO | disclosed |