Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 9/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 5/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.38 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.38 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.38 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20030059 | 1.00 | ALDH1A1 (0.40) | ALDH1A1TSHRHPGDKDM4EATM | |
| SCHEMBL20029898 | 1.00 | ALDH1A1 (0.40) | ALDH1A1TSHRHPGDKDM4EATM | |
| SCHEMBL20030033 | 0.99 | ALDH1A1 (0.40) | ALDH1A1TSHRHPGDKDM4EATM | |
| SCHEMBL20030032 | 0.98 | ALDH1A1 (0.39) | ALDH1A1TSHRHPGDKDM4EATM | |
| SCHEMBL20030027 | 0.98 | ALDH1A1 (0.39) | ALDH1A1TSHRHPGDKDM4EATM | |
| SCHEMBL23789573 | 0.98 | ALDH1A1 (0.39) | ALDH1A1TSHRHPGDKDM4EATM | |
| SCHEMBL20030155 | 0.98 | ALDH1A1 (0.39) | ALDH1A1TSHRHPGDKDM4EATM | |
| SCHEMBL20030169 | 0.98 | KDM4E (0.39) | ALDH1A1TSHRHPGDKDM4EATM | |
| SCHEMBL20024186 | 0.97 | ALDH1A1 (0.39) | ALDH1A1TSHRHPGDKDM4EATM | |
| SCHEMBL22006458 | 0.97 | ALDH1A1 (0.39) | ALDH1A1TSHRHPGDKDM4EATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115232137-A | Compound having diaza dibenzofuran or diaza dibenzothiophene structure | 默克专利有限公司 | 2022-10-25 | — | — | CN | disclosed |
| CN-115160329-A | Compounds having a structure of diaza-dibenzofuran or diaza-dibenzothiophene | 默克专利有限公司 | 2022-10-11 | — | — | CN | disclosed |
| CN-115160328-A | Compounds having a structure of diaza-dibenzofuran or diaza-dibenzothiophene | 默克专利有限公司 | 2022-10-11 | — | — | CN | disclosed |
| CN-109689658-B | Compounds having a structure of diaza-dibenzofuran or diaza-dibenzothiophene | 默克专利有限公司 | 2022-07-26 | — | — | CN | disclosed |