Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 15/20 | 0.81 |
| ▸ | F11 | P03951 | 7/20 | 0.79 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22981918 | 1.00 | KLKB1 (0.81) | KLKB1F11 | |
| SCHEMBL29405129 | 0.96 | KLKB1 (0.83) | KLKB1F11 | |
| SCHEMBL29407550 | 0.96 | KLKB1 (0.83) | KLKB1F11 | |
| SCHEMBL22981556 | 0.96 | KLKB1 (0.83) | KLKB1F11 | |
| SCHEMBL22993179 | 0.92 | F11 (0.84) | KLKB1F11 | |
| SCHEMBL26227507 | 0.92 | KLKB1 (0.84) | KLKB1F11 | |
| SCHEMBL29697514 | 0.92 | KLKB1 (0.84) | KLKB1F11 | |
| SCHEMBL22981502 | 0.91 | F11 (0.85) | KLKB1F11 | |
| SCHEMBL29407281 | 0.91 | F11 (0.85) | KLKB1F11 | |
| SCHEMBL29407533 | 0.90 | KLKB1 (1.00) | KLKB1F11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4010333-A1 | PLASMA KALLIKREIN INHIBITORS | Kalvista Pharmaceuticals Limited (GB) | 2022-06-15 | — | — | EP | claimed |