Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 7/20 | 0.69 |
| ▸ | LCK | P06239 | 16/20 | 0.67 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.67 |
| ▸ | EGFR | P00533 | 1/20 | 0.67 |
| ▸ | FYN | P06241 | 1/20 | 0.67 |
| ▸ | HCK | P08631 | 1/20 | 0.67 |
| ▸ | SRC | P12931 | 1/20 | 0.67 |
| ▸ | JAK3 | P52333 | 1/20 | 0.67 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.67 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1539936 | 1.00 | MAPK14 (0.69) | MAPK14LCKMAPK13EGFRFYN | |
| SCHEMBL31052681 | 0.90 | LCK (0.60) | MAPK14LCKMAPK13EGFRFYN | |
| SCHEMBL14416598 | 0.88 | MAPK14 (0.70) | MAPK14LCKMAPK13EGFRFYN | |
| SCHEMBL31728413 | 0.88 | MAPK14 (0.70) | MAPK14LCKMAPK13EGFRFYN | |
| SCHEMBL1147098 | 0.88 | MAPK14 (0.70) | MAPK14LCKMAPK13EGFRFYN | |
| SCHEMBL1540030 | 0.86 | MAPK14 (0.67) | MAPK14LCKMAPK13EGFRFYN | |
| SCHEMBL29616014 | 0.86 | MAPK14 (0.67) | MAPK14LCKMAPK13EGFRFYN | |
| SCHEMBL774486 | 0.85 | MAPK14 (0.77) | MAPK14LCKMAPK13EGFRFYN | |
| SCHEMBL2774894 | 0.85 | LCK (0.83) | MAPK14LCKMAPK13EGFRFYN | |
| SCHEMBL15846536 | 0.84 | MAPK14 (0.65) | MAPK14LCKMAPK13EGFRFYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114605348-B | Compounds having HDAC inhibitory activity, preparation method, compositions and uses thereof | 北京鑫开元医药科技有限公司 | 2022-08-16 | — | — | CN | disclosed |
| CN-114605348-A | Compounds having HDAC inhibitory activity, methods of making, compositions, and uses thereof | 北京鑫开元医药科技有限公司 | 2022-06-10 | — | — | CN | disclosed |