Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | SCN1A | P35498 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.39 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 3/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | HTR1B | P28222 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3732127 | 1.00 | SLC18A3 (0.50) | SLC18A3SIGMAR1TSHRADRA2AMEN1 | |
| SCHEMBL31322262 | 0.82 | SLC18A3 (0.53) | SLC18A3SIGMAR1TSHRMEN1LMNA | |
| SCHEMBL2962509 | 0.79 | TSHR (0.54) | SLC18A3SIGMAR1TSHRADRA2AMEN1 | |
| SCHEMBL1195857 | 0.73 | TSHR (0.64) | SLC18A3SIGMAR1TSHRADRA2AMEN1 | |
| SCHEMBL28721035 | 0.71 | TSHR (0.48) | SLC18A3SIGMAR1TSHRADRA2ASLC6A2 | |
| SCHEMBL21989278 | 0.71 | TSHR (0.43) | SLC18A3SIGMAR1TSHRADRA2ASLC6A2 | |
| SCHEMBL10846742 | 0.68 | MAOB (0.45) | SLC18A3SIGMAR1TSHRMEN1CYP2D6 | |
| SCHEMBL28414 | 0.68 | TSHR (0.56) | TSHRMEN1KMT2ASLC6A2SLC6A4 | |
| SCHEMBL17414393 | 0.68 | TSHR (0.56) | TSHRMEN1KMT2ASLC6A2SLC6A4 | |
| SCHEMBL9742553 | 0.68 | GBA1 (0.55) | SLC18A3SIGMAR1HRH1SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114605272-A | Preparation method of (R) -fluoxetine and derivative thereof | 中国科学技术大学 | 2022-06-10 | — | — | CN | disclosed |