Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SCN1A | P35498 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.42 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8538844 | 0.82 | DRD2 (0.65) | DRD2DRD3HTR1AHTR2A | |
| SCHEMBL1626963 | 0.82 | DRD2 (0.65) | DRD2DRD3HTR1AHTR2A | |
| SCHEMBL357358 | 0.82 | DRD2 (0.65) | DRD2DRD3HTR1AHTR2A | |
| SCHEMBL3732127 | 0.82 | SLC18A3 (0.50) | SLC18A3SIGMAR1TSHRSLC6A2SLC6A3 | |
| SCHEMBL4536932 | 0.82 | DRD2 (0.65) | DRD2DRD3HTR1AHTR2A | |
| SCHEMBL29698175 | 0.82 | SLC18A3 (0.50) | SLC18A3SIGMAR1TSHRSLC6A2SLC6A3 | |
| SCHEMBL31322222 | 0.81 | — | — | |
| SCHEMBL2602803 | 0.81 | — | — | |
| SCHEMBL1195857 | 0.81 | TSHR (0.64) | SLC18A3SIGMAR1TSHRSLC6A2SLC6A3 | |
| SCHEMBL28845061 | 0.81 | DRD2 (0.63) | DRD2DRD3HTR1AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025038930-A1 | AZEPANE AND PYRROLIDINE COMPOUNDS AND USES THEREOF | XENON PHARMACEUTICALS, INC. (CA) | 2025-02-20 | — | — | WO | disclosed |