Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL3 | Q96JM7 | 11/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 9/20 | 0.39 |
| ▸ | L3MBTL4 | Q8NA19 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MBTD1 | Q05BQ5 | 4/20 | 0.38 |
| ▸ | ACACB | O00763 | 2/20 | 0.38 |
| ▸ | ACACA | Q13085 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TP53BP1 | Q12888 | 2/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1719881 | 1.00 | L3MBTL3 (0.39) | L3MBTL3L3MBTL1L3MBTL4MAPTTDP1 | |
| SCHEMBL1719447 | 0.93 | L3MBTL3 (0.39) | L3MBTL3L3MBTL1L3MBTL4MAPTTDP1 | |
| SCHEMBL1720283 | 0.91 | ACACB (0.38) | L3MBTL3L3MBTL1L3MBTL4MAPTTDP1 | |
| SCHEMBL1720182 | 0.90 | MAPT (0.38) | L3MBTL3L3MBTL1L3MBTL4MAPTTDP1 | |
| SCHEMBL1720509 | 0.88 | L3MBTL3 (0.36) | L3MBTL3L3MBTL1L3MBTL4MAPTTDP1 | |
| SCHEMBL1719045 | 0.88 | L3MBTL3 (0.41) | L3MBTL3L3MBTL1L3MBTL4MAPTTDP1 | |
| SCHEMBL1719250 | 0.88 | L3MBTL3 (0.41) | L3MBTL3L3MBTL1L3MBTL4MAPTTDP1 | |
| SCHEMBL1891032 | 0.87 | L3MBTL3 (0.40) | L3MBTL3L3MBTL1L3MBTL4MAPTTDP1 | |
| SCHEMBL10207105 | 0.87 | L3MBTL3 (0.40) | L3MBTL3L3MBTL1L3MBTL4MAPTTDP1 | |
| SCHEMBL1720087 | 0.85 | ACACB (0.41) | L3MBTL3L3MBTL1L3MBTL4MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118076602-A | Heteroaryl-acetylenes, pharmaceutical compositions thereof and their therapeutic uses | 嘉兴优博生物技术有限公司 | 2024-05-24 | — | — | CN | disclosed |
| EP-4255903-A1 | HETEROARYL-ACETYLENES, PHARMACEUTICAL COMPOSITIONS THEREOF, AND THEIR THERAPEUTIC APPLICATIONS | Eubulus Biotherapeutics Inc. (CN) | 2023-10-11 | — | — | EP | disclosed |
| WO-2022117064-A1 | HETEROARYL-ACETYLENES, PHARMACEUTICAL COMPOSITIONS THEREOF, AND THEIR THERAPEUTIC APPLICATIONS | EUBULUS BIOTHERAPEUTICS INC. (CN) | 2022-06-09 | — | — | WO | disclosed |