Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2372434 | 1.00 | CFTR (0.69) | CFTRACVR1 | |
| SCHEMBL2372606 | 0.82 | CFTR (1.00) | CFTR | |
| SCHEMBL2371649 | 0.82 | CFTR (1.00) | CFTR | |
| SCHEMBL2372600 | 0.82 | CFTR (1.00) | CFTR | |
| SCHEMBL14784661 | 0.77 | P2RX7 (0.40) | CFTR | |
| SCHEMBL22791161 | 0.75 | CFTR (0.43) | CFTRACVR1 | |
| SCHEMBL2373060 | 0.73 | CFTR (0.80) | CFTR | |
| SCHEMBL2372326 | 0.72 | CFTR (1.00) | CFTR | |
| SCHEMBL2372386 | 0.72 | CFTR (1.00) | CFTR | |
| SCHEMBL2371672 | 0.72 | CFTR (1.00) | CFTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3980121-A1 | PYRIDINE AND PYRAZINE DERIVATIVE FOR THE TREATMENT OF CF, COPD, AND BRONCHIECTASIS | Novartis AG (CH) | 2022-04-13 | — | — | EP | disclosed |