SCHEMBL29699362

SCHEMBL29699362

N=C(N)c1ccc2nc(-c3ccc(-c4nc5ccc(C(=N)N)cc5[nH]4)o3)[nH]c2c1

nearest known ligand 0.71

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
F2 P00734 9/20 0.68
F10 P00742 9/20 0.68
F7 P08709 3/20 0.68
PLAU P00749 7/20 0.66
PRSS1 P07477 7/20 0.66
PLG P00747 6/20 0.63
PLAT P00750 5/20 0.63
PRSS2 P07478 2/20 0.61
PRSS3 P35030 2/20 0.61
HPN P05981 1/20 0.61
TPSAB1 Q15661 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14259601 1.00 F2 (0.68) F2F10F7PLAUPRSS1
SCHEMBL12348382 0.93 PLAU (0.62) F2F10F7PLAUPRSS1
SCHEMBL13167152 0.92 F2 (0.59) F2F10F7PLAUPRSS1
SCHEMBL13167141 0.92 PLAU (0.62) F2F10F7PLAUPRSS1
SCHEMBL30689279 0.89 F10 (0.61) F2F10F7PLAUPRSS1
SCHEMBL14599572 0.89 F10 (0.61) F2F10F7PLAUPRSS1
SCHEMBL549166 0.88 F2 (0.56) F2F10F7PLAUPRSS1
Hydrochloric Acid SCHEMBL11294147 0.87 F2 (0.55) F2F10F7PLAUPRSS1
SCHEMBL13882980 0.85 PLAU (0.55) F2F10F7PLAUPRSS1
SCHEMBL13167166 0.85 PLAU (0.53) F2F10F7PLAUPRSS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250101435-A1 COMPOSITIONS AND METHODS TO TREAT CANCER NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH, INC. 2025-03-27 US disclosed
WO-2024247428-A1 FOOD PROPOSAL DEVICE, FOOD PROPOSAL METHOD, AND PROGRAM パナソニックIPマネジメント株式会社 2024-12-05 WO disclosed
WO-2024089820-A1 INFORMATION DISTRIBUTION DEVICE, PREDICTION SYSTEM, INFORMATION DISTRIBUTION METHOD, AND PROGRAM 日本電信電話株式会社 2024-05-02 WO disclosed
US-20240052354-A1 COMPOSITIONS AND METHODS TO TREAT CANCER NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH, INC. 2024-02-15 US disclosed
WO-2023170803-A1 DESIGN AUTOMATION DEVICE, DESIGN AUTOMATION SYSTEM, DESIGN AUTOMATION METHOD, AND DESIGN AUTOMATION PROGRAM 三菱電機株式会社 2023-09-14 WO disclosed
WO-2023058310-A1 ARTICLE MANAGEMENT SYSTEM, METHOD AND READING DEVICE キヤノン株式会社 2023-04-13 WO disclosed
WO-2023286425-A1 DEVICE FOR ASSISTING WITH CHANGING OPERATION PLAN, METHOD FOR ASSISTING WITH CHANGING OPERATION PLAN, AND TRAIN OPERATION MANAGEMENT SYSTEM 株式会社日立製作所 2023-01-19 WO disclosed
US-11530413-B2 Compositions and methods to treat cancer NOVARTIS AG (CH) 2022-12-20 US disclosed
WO-2022234693-A1 INFORMATION PROCESSING DEVICE, INFORMATION PROCESSING METHOD, AND PROGRAM ソニーグループ株式会社 2022-11-10 WO disclosed
EP-4085919-A2 COMPOSITIONS AND METHODS TO TREAT CANCER Novartis AG (CH) 2022-11-09 EP disclosed
CN-110317496-B Aqueous inkjet composition 精工爱普生株式会社 2022-10-21 CN disclosed
WO-2022210352-A1 ARTICLE MANAGEMENT SYSTEM, ARTICLE MANAGEMENT METHOD, READING DEVICE, AND INFORMATION PROCESSING DEVICE キヤノン株式会社 2022-10-06 WO disclosed
US-11384249-B2 Aqueous ink jet composition SEIKO EPSON CORPORATION (JP) 2022-07-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240052354-A1 COMPOSITIONS AND METHODS TO TREAT CANCER TP53, BRCA1, NTPCR F2 3780/4885F10 3393/4885F7 3326/4885
US-11530413-B2 Compositions and methods to treat cancer TP53, BRCA1, NTPCR F2 3780/4885F10 3393/4885F7 3326/4885
US-20250101435-A1 COMPOSITIONS AND METHODS TO TREAT CANCER TP53, BRCA1, NTPCR F2 3780/4885F10 3393/4885F7 3326/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.