Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 9/20 | 0.53 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.53 |
| ▸ | PLG | P00747 | 8/20 | 0.52 |
| ▸ | F2 | P00734 | 5/20 | 0.52 |
| ▸ | F10 | P00742 | 5/20 | 0.52 |
| ▸ | PLAT | P00750 | 4/20 | 0.52 |
| ▸ | F7 | P08709 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | HPN | P05981 | 1/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12348382 | 0.86 | PLAU (0.62) | PLAUPRSS1PLGF2F10 | |
| SCHEMBL5408978 | 0.85 | PLAU (0.65) | PLAUPRSS1PLGF2F10 | |
| SCHEMBL13167141 | 0.85 | PLAU (0.62) | PLAUPRSS1PLGF2F10 | |
| SCHEMBL29699362 | 0.85 | F2 (0.68) | PLAUPRSS1PLGF2F10 | |
| SCHEMBL14259601 | 0.85 | F2 (0.68) | PLAUPRSS1PLGF2F10 | |
| SCHEMBL13882980 | 0.79 | PLAU (0.55) | PLAUPRSS1PLGF2F10 | |
| SCHEMBL13167152 | 0.78 | F2 (0.59) | PLAUPRSS1PLGF2F10 | |
| SCHEMBL14599560 | 0.78 | PLAU (0.63) | PLAUPRSS1PLGF2F10 | |
| SCHEMBL5408990 | 0.77 | PLAU (0.52) | PLAUPRSS1PLGF2F10 | |
| SCHEMBL14519390 | 0.76 | PLAU (0.86) | PLAUPRSS1PLGF2F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100249175-A1 | Dicationic compounds which selectively recognize G-quadruplex DNA | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. | 2010-09-30 | — | — | US | disclosed |
| US-20100249175-A1 | Dicationic compounds which selectively recognize G-quadruplex DNA | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. | 2010-09-30 | — | — | US | disclosed |
| EP-1792613-A2 | Dicationic compounds which selectively recognize G-quadruplex DNA | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2007-06-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100249175-A1 | Dicationic compounds which selectively recognize G-quadruplex DNA | DDB1, DNA2, SSBP1 | PLAU 4677/4885PRSS1 4661/4885PLG 3752/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.