Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | ESR1 | P03372 | 2/20 | 0.58 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | FNTA | P49354 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9851427 | 0.90 | KMT2A (0.64) | POLBKMT2AESR1ESR2MEN1 | |
| SCHEMBL28731362 | 0.89 | KMT2A (0.67) | POLBKMT2AESR1ESR2MEN1 | |
| SCHEMBL2833933 | 0.89 | KMT2A (0.57) | POLBKMT2AESR1ESR2MEN1 | |
| SCHEMBL30607253 | 0.86 | ESR1 (0.58) | POLBKMT2AESR1ESR2MEN1 | |
| SCHEMBL5150486 | 0.86 | ESR1 (0.58) | POLBKMT2AESR1ESR2MEN1 | |
| SCHEMBL6349146 | 0.84 | POLB (0.73) | POLBKMT2AESR1ESR2MEN1 | |
| SCHEMBL29185418 | 0.83 | ESR1 (0.60) | POLBKMT2AESR1ESR2MEN1 | |
| SCHEMBL28731649 | 0.83 | KMT2A (0.73) | POLBKMT2AESR1ESR2MEN1 | |
| SCHEMBL8431592 | 0.82 | KMT2A (0.68) | POLBKMT2AESR1ESR2MEN1 | |
| SCHEMBL27606607 | 0.82 | ALDH1A1 (0.68) | POLBKMT2AESR1MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220170904-A1 | SYSTEMS AND METHODS FOR MONITORING BIOLOGICAL TISSUE DEGRADATION | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2022-06-02 | — | — | US | disclosed |