Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VKORC1 | Q9BQB6 | 2/20 | 0.74 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.56 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | IKBKB | O14920 | 1/20 | 0.51 |
| ▸ | MGAM | O43451 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | SI | P14410 | 3/20 | 0.51 |
| ▸ | MGAM2 | Q2M2H8 | 3/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | SNCA | P37840 | 1/20 | 0.46 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5309695 | 0.85 | VKORC1 (1.00) | VKORC1ALOX15MAOAMGAMGAA | |
| SCHEMBL5309688 | 0.85 | VKORC1 (1.00) | VKORC1ALOX15MAOAMGAMGAA | |
| SCHEMBL28444444 | 0.85 | VKORC1 (0.67) | VKORC1ALOX15MAOAIKBKBMGAM | |
| SCHEMBL28552754 | 0.85 | VKORC1 (0.67) | VKORC1ALOX15MAOAIKBKBMGAM | |
| SCHEMBL16768172 | 0.84 | VKORC1 (0.97) | VKORC1ALOX15MAOAMGAMGAA | |
| SCHEMBL28369886 | 0.84 | VKORC1 (0.65) | VKORC1ALOX15MAOAIKBKBMGAM | |
| SCHEMBL16924700 | 0.74 | VKORC1 (0.63) | VKORC1ALOX15MAOAIKBKBMGAM | |
| Aurachin D SCHEMBL16552860 | 0.74 | SLC2A1 (0.64) | VKORC1ALOX15MAOAPTPN1PGR | |
| Aurachin D SCHEMBL29456185 | 0.74 | SLC2A1 (0.64) | VKORC1ALOX15MAOAPTPN1PGR | |
| Aurachin D SCHEMBL15094902 | 0.74 | SLC2A1 (0.64) | VKORC1ALOX15MAOAPTPN1PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111643507-B | Application of fernasenol in treating pulmonary fibrosis | 朱有建 | 2022-06-17 | — | — | CN | disclosed |
| CN-111743903-B | Application of taraxacil in treating pulmonary fibrosis | 朱有建 | 2022-06-14 | — | — | CN | disclosed |