SCHEMBL28369886

SCHEMBL28369886

CC(C)=CCC/C(C)=C/Cc1c(-c2ccccc2)oc2ccccc2c1=O

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ VKORC1 Q9BQB6 2/20 0.65
▸ ABCG2 Q9UNQ0 2/20 0.52
▸ ALOX15 P16050 5/20 0.50
▸ CYP19A1 P11511 2/20 0.50
▸ MGAM O43451 1/20 0.49
▸ GAA P10253 1/20 0.49
▸ SI P14410 1/20 0.49
▸ PTPN1 P18031 1/20 0.49
▸ MGAM2 Q2M2H8 1/20 0.49
▸ MAOA P21397 1/20 0.48
▸ KDM4E B2RXH2 1/20 0.47
▸ MEN1 O00255 1/20 0.47
▸ CA12 O43570 1/20 0.47
▸ CA1 P00915 1/20 0.47
▸ CA2 P00918 1/20 0.47
▸ LMNA P02545 1/20 0.47
▸ TP53 P04637 1/20 0.47
▸ ABCB1 P08183 1/20 0.47
▸ CYP3A4 P08684 1/20 0.47
▸ CALM1 P0DP23 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28444444 0.99 VKORC1 (0.67) VKORC1ABCG2ALOX15CYP19A1MGAM
SCHEMBL28552754 0.99 VKORC1 (0.67) VKORC1ABCG2ALOX15CYP19A1MGAM
SCHEMBL623887 0.89 VKORC1 (0.59) VKORC1ABCG2ALOX15CYP19A1GAA
SCHEMBL27971484 0.88 VKORC1 (0.51) VKORC1ABCG2ALOX15CYP19A1MGAM
SCHEMBL29699624 0.84 VKORC1 (0.74) VKORC1ABCG2ALOX15CYP19A1MGAM
SCHEMBL16768172 0.80 VKORC1 (0.97) VKORC1ALOX15MGAMGAASI
SCHEMBL27006404 0.79 PTPN1 (0.53) VKORC1ABCG2CYP19A1MGAMGAA
SCHEMBL5309688 0.79 VKORC1 (1.00) VKORC1ALOX15MGAMGAASI
SCHEMBL5309695 0.79 VKORC1 (1.00) VKORC1ALOX15MGAMGAASI
SCHEMBL9019380 0.76 DDR2 (0.60) ABCG2ALOX15CYP19A1GAAPTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111467391-B Application of geranylflavone A in preparation of medicine for promoting wound healing 汉义生物科技(北京)有限公司 2023-03-03 — — CN claimed
CN-111467391-B Application of geranylflavone A in preparation of medicine for promoting wound healing 汉义生物科技(北京)有限公司 2023-03-03 — — CN disclosed
CN-114653092-A Extraction method of industrial hemp, obtained industrial hemp essential oil and application thereof 云南汉盟制药有限公司 2022-06-24 — — CN disclosed
US-20220079916-A1 USE OF GERANYLFLAVONE A IN PREPARATION OF DRUG FOR PROMOTING HEALING OF WOUNDS HANYI BIO-TECHNOLOGY COMPANY LTD. (CN) 2022-03-17 — — US disclosed
EP-3888649-A4 USE OF GERANYLFLAVONE A IN PREPARATION OF DRUG FOR PROMOTING HEALING OF WOUNDS Hanyi Bio-Technology Company Ltd. (CN) 2022-01-19 — — EP disclosed
CN-111956641-B Flavonoid compound composition and preparation method thereof 云南汉盟制药有限公司 2021-11-02 — — CN disclosed
CN-111961021-B Separation and purification process of geranylflavone A 云南汉盟制药有限公司 2021-08-03 — — CN disclosed
CN-111956641-A Flavonoid compound composition and preparation method thereof 云南汉盟制药有限公司 2020-11-20 — — CN disclosed
CN-111961021-A Separation and purification process of high-purity geranylflavonoid A 云南汉盟制药有限公司 2020-11-20 — — CN disclosed
CN-111467391-A Application of geranylflavone A in preparation of medicine for promoting wound healing 汉义生物科技(北京)有限公司 2020-07-31 — — CN disclosed
CN-107987047-B Geranylflavone compound extracted from cortex Mori, and its preparation method and application 成都普思生物科技股份有限公司 2020-03-20 — — CN disclosed
CN-107987047-B Geranylflavone compound extracted from cortex Mori, and its preparation method and application 成都普思生物科技股份有限公司 2020-03-20 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220079916-A1 USE OF GERANYLFLAVONE A IN PREPARATION OF DRUG FOR PROMOTING HEALING OF WOUNDS AGER, GID4, MFN2 VKORC1 2131/4885ABCG2 3263/4885ALOX15 131/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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